PMID- 22900218 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20120823 LR - 20211021 IS - 2090-6730 (Electronic) IS - 2090-6722 (Print) VI - 2012 DP - 2012 TI - Isolated foveal hypoplasia: tomographic, angiographic and autofluorescence patterns. PG - 864958 LID - 10.1155/2012/864958 [doi] LID - 864958 AB - Purpose. To report clinical aspects, tomographic, angiographic, and autofluorescence patterns of two cases of isolated foveal hypoplasia. Methods. Foveal hypoplasia was found in a 23-year-old male patient and in a 64-year-old woman with impaired visual acuity of unknown etiology that remained unchanged for years. Results. In the first case, spectral-domain optical coherence tomography (SD-OCT) showed reduced foveal pit and continuity of inner retinal layers in the fovea. Photoreceptor layer had a normal thickness centrally. The foveal avascular zone (FAZ) was absent in the flourescein angiogram (FA). Fundus autofluorescence showed reduced foveal attenuation of autofluorescence. In the second patient, there was the same pattern in SD-OCT, with normal aspect in FA and only a slightly reduced foveal attenuation of autofluorescence. Conclusion. OCT, as a noninvasive and quick method, is helpful in the diagnosis of foveal hypoplasia. FA and fundus autofluorescence were less sensitive. FAU - Mota, Agata AU - Mota A AD - Department of Ophthalmology, Hospital S. Joao, Alameda Prof. Hernani Monteiro, 4200-319 Porto, Portugal. FAU - Fonseca, Sofia AU - Fonseca S FAU - Carneiro, Angela AU - Carneiro A FAU - Magalhaes, Augusto AU - Magalhaes A FAU - Brandao, Elisete AU - Brandao E FAU - Falcao-Reis, Fernando AU - Falcao-Reis F LA - eng PT - Journal Article DEP - 20120731 PL - United States TA - Case Rep Ophthalmol Med JT - Case reports in ophthalmological medicine JID - 101581018 PMC - PMC3415089 EDAT- 2012/08/18 06:00 MHDA- 2012/08/18 06:01 PMCR- 2012/07/31 CRDT- 2012/08/18 06:00 PHST- 2012/05/15 00:00 [received] PHST- 2012/06/28 00:00 [accepted] PHST- 2012/08/18 06:00 [entrez] PHST- 2012/08/18 06:00 [pubmed] PHST- 2012/08/18 06:01 [medline] PHST- 2012/07/31 00:00 [pmc-release] AID - 10.1155/2012/864958 [doi] PST - ppublish SO - Case Rep Ophthalmol Med. 2012;2012:864958. doi: 10.1155/2012/864958. Epub 2012 Jul 31.