PMID- 22902265
OWN - NLM
STAT- MEDLINE
DCOM- 20130116
LR  - 20120917
IS  - 1532-3064 (Electronic)
IS  - 0954-6111 (Linking)
VI  - 106
IP  - 11
DP  - 2012 Nov
TI  - Does upper extremity exercise improve dyspnea in patients with COPD? A 
      meta-analysis.
PG  - 1517-25
LID - S0954-6111(12)00293-4 [pii]
LID - 10.1016/j.rmed.2012.08.002 [doi]
AB  - BACKGROUND: Although unsupported upper extremity exercise (UUEE) is recommended 
      in the guidelines for pulmonary rehabilitation (PR), it is controversial whether 
      UUEE improves dyspnea in patients with COPD. The present study conducted a 
      meta-analysis of randomized controlled trials to clarify whether UUEE could 
      improve dyspnea in COPD patients. METHODS: A computerized search through PubMed 
      and Embase (up to Mar 2012) was performed to obtain sample studies. 
      Methodological quality was assessed using the PEDro scale. Weighted mean 
      differences (WMDs), and 95% confidence intervals (CIs) were calculated and 
      heterogeneity was assessed with the I(2) test. The overall effect sizes were 
      compared with the minimum clinically important difference (MCID). RESULTS: 240 
      patients from 7 studies were included in this meta-analysis. The mean PEDro score 
      was 7.0 (SD = 1.7). The results indicated UUEE relieved dyspnea and arm fatigue 
      during activities of daily living (ADL) (WMD = -0.58, -0.55 scores; 95% 
      CI = -1.13 to -0.02, -1.08 to -0.01), however, the overall treatment effects were 
      lower than the MCID of 1 unit for the Borg scale. There was no statistical 
      significance for dyspnea and arm fatigue during intervention (WMD = -0.34, 0.24 
      scores; 95% CI = -0.78 to 0.09, -0.33 to 0.81). CONCLUSIONS: UUEE can relieve 
      dyspnea and arm fatigue in patients with COPD during ADL and should be included 
      in the PR program, however, there is currently a lack of clinical evidence to 
      support UUEE relieving dyspnea and arm fatigue. Further study is urgent to 
      investigate these effects of UUEE.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Pan, Lei
AU  - Pan L
AD  - State Key Laboratory of Respiratory Disease, First Affiliated Hospital, Guangzhou 
      Medical College, 151 Yanjiang Road, Guangzhou 510120, PR China. Electronic 
      address: zypl781102@163.com
FAU - Guo, Yong Zhong
AU  - Guo YZ
FAU - Yan, Jun Hong
AU  - Yan JH
FAU - Zhang, Wen Xiao
AU  - Zhang WX
FAU - Sun, Jian
AU  - Sun J
FAU - Li, Bao Wei
AU  - Li BW
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20120816
PL  - England
TA  - Respir Med
JT  - Respiratory medicine
JID - 8908438
SB  - IM
MH  - Activities of Daily Living
MH  - Arm
MH  - Dyspnea/*therapy
MH  - Exercise Therapy/*methods
MH  - Fatigue/prevention & control
MH  - Humans
MH  - Pulmonary Disease, Chronic Obstructive/*rehabilitation
MH  - Quality of Life
MH  - Randomized Controlled Trials as Topic
EDAT- 2012/08/21 06:00
MHDA- 2013/01/17 06:00
CRDT- 2012/08/21 06:00
PHST- 2012/05/22 00:00 [received]
PHST- 2012/08/01 00:00 [accepted]
PHST- 2012/08/21 06:00 [entrez]
PHST- 2012/08/21 06:00 [pubmed]
PHST- 2013/01/17 06:00 [medline]
AID - S0954-6111(12)00293-4 [pii]
AID - 10.1016/j.rmed.2012.08.002 [doi]
PST - ppublish
SO  - Respir Med. 2012 Nov;106(11):1517-25. doi: 10.1016/j.rmed.2012.08.002. Epub 2012 
      Aug 16.