PMID- 22906246
OWN - NLM
STAT- MEDLINE
DCOM- 20130115
LR  - 20211021
IS  - 1879-1883 (Electronic)
IS  - 0002-9610 (Print)
IS  - 0002-9610 (Linking)
VI  - 204
IP  - 5
DP  - 2012 Nov
TI  - Poor survival for veterans with pathologic stage I non-small-cell lung cancer.
PG  - 637-42
LID - S0002-9610(12)00354-6 [pii]
LID - 10.1016/j.amjsurg.2012.07.008 [doi]
AB  - BACKGROUND: Pathologic stage (pStage) IA and IB non-small-cell lung cancer 
      (NSCLC) has a median survival time of 119 and 81 months, respectively. We 
      describe the outcomes of veterans with pStage I NSCLC. METHODS: A retrospective 
      review of 78 patients with pStage I NSCLC who underwent cancer resection was 
      performed at the Tennessee Valley Veterans Affairs Hospital between 2005 and 
      2010. All-cause 30-day, 90-day, and overall mortality were determined. Survival 
      was assessed with the Kaplan-Meier and Cox proportional hazards methods. RESULTS: 
      There were 55 (71%) pStage IA and 23 (29%) IB patients. Thirty- and 90-day 
      mortality was 3.8% (3 of 78) and 6.4% (5 of 78), respectively. Median survival 
      was 59 and 28 months for pStage 1A and 1B, respectively. Postoperative events 
      were associated with impaired survival on multivariable analysis (hazard ratio, 
      1.26, P = .03). CONCLUSIONS: Veterans with pStage I NSCLC at our institution have 
      poorer survival than the general population. More research is needed to determine 
      the etiology of this disparity.
CI  - Published by Elsevier Inc.
FAU - St Julien, Jamii B
AU  - St Julien JB
AD  - Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, 
      TN 37232, USA.
FAU - Pinkerman, Rhonda
AU  - Pinkerman R
FAU - Aldrich, Melinda C
AU  - Aldrich MC
FAU - Chen, Heidi
AU  - Chen H
FAU - Deppen, Stephen A
AU  - Deppen SA
FAU - Callaway-Lane, Carol
AU  - Callaway-Lane C
FAU - Massion, Pierre
AU  - Massion P
FAU - Putnam, Joe B
AU  - Putnam JB
FAU - Lambright, Eric S
AU  - Lambright ES
FAU - Nesbitt, Jonathan C
AU  - Nesbitt JC
FAU - Grogan, Eric L
AU  - Grogan EL
LA  - eng
GR  - IK2 HX000758/HX/HSRD VA/United States
GR  - T32 CA106183/CA/NCI NIH HHS/United States
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20120818
PL  - United States
TA  - Am J Surg
JT  - American journal of surgery
JID - 0370473
SB  - IM
MH  - Aged
MH  - Carcinoma, Non-Small-Cell Lung/mortality/pathology/*surgery
MH  - Health Status Disparities
MH  - Humans
MH  - Lung Neoplasms/mortality/pathology/*surgery
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Neoplasm Staging
MH  - Pneumonectomy/*mortality
MH  - Postoperative Complications/mortality
MH  - Retrospective Studies
MH  - Survival Analysis
MH  - Tennessee
MH  - Treatment Outcome
MH  - Veterans Health/*statistics & numerical data
PMC - PMC3766956
MID - NIHMS499553
EDAT- 2012/08/22 06:00
MHDA- 2013/01/16 06:00
PMCR- 2013/11/01
CRDT- 2012/08/22 06:00
PHST- 2012/04/05 00:00 [received]
PHST- 2012/07/10 00:00 [revised]
PHST- 2012/07/10 00:00 [accepted]
PHST- 2012/08/22 06:00 [entrez]
PHST- 2012/08/22 06:00 [pubmed]
PHST- 2013/01/16 06:00 [medline]
PHST- 2013/11/01 00:00 [pmc-release]
AID - S0002-9610(12)00354-6 [pii]
AID - 10.1016/j.amjsurg.2012.07.008 [doi]
PST - ppublish
SO  - Am J Surg. 2012 Nov;204(5):637-42. doi: 10.1016/j.amjsurg.2012.07.008. Epub 2012 
      Aug 18.