PMID- 22907143
OWN - NLM
STAT- MEDLINE
DCOM- 20121026
LR  - 20120821
IS  - 1423-0259 (Electronic)
IS  - 0030-3747 (Linking)
VI  - 48 Suppl 1
DP  - 2012
TI  - Strategies for following dry age-related macular degeneration.
PG  - 6-10
LID - 10.1159/000339841 [doi]
AB  - Spectral domain optical coherence tomography (SDOCT) provides a novel strategy 
      for imaging and monitoring progression in patients with age-related macular 
      degeneration (AMD). The advantage of SDOCT over other imaging modalities or 
      functional tests is that one modality can be used to image both drusen and 
      geographic atrophy while obtaining reproducible, quantitative data on both drusen 
      morphology and the area of geographic atrophy. Moreover, this strategy enables 
      the clinician to follow the disease as it progresses from drusen to both 
      geographic atrophy and choroidal neovascularization. No other imaging modality is 
      able to quantitatively assess all forms of AMD. This unique feature of SDOCT 
      makes it the ideal imaging modality for monitoring patients with AMD, providing 
      routine care, and for following patients in clinical trials designed to assess 
      the efficacy of new drugs for the treatment of dry AMD.
CI  - Copyright (c) 2012 S. Karger AG, Basel.
FAU - Yehoshua, Zohar
AU  - Yehoshua Z
AD  - Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami 
      Miller School of Medicine, Miami, Fla 33136, USA.
FAU - Rosenfeld, Philip J
AU  - Rosenfeld PJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120821
PL  - Switzerland
TA  - Ophthalmic Res
JT  - Ophthalmic research
JID - 0267442
SB  - IM
MH  - *Diagnostic Techniques, Ophthalmological
MH  - Disease Progression
MH  - Follow-Up Studies
MH  - Geographic Atrophy/*diagnosis
MH  - Humans
MH  - Retina/pathology
MH  - Retinal Drusen/*diagnosis
MH  - *Tomography, Optical Coherence
EDAT- 2012/08/29 06:00
MHDA- 2012/10/27 06:00
CRDT- 2012/08/22 06:00
PHST- 2012/08/22 06:00 [entrez]
PHST- 2012/08/29 06:00 [pubmed]
PHST- 2012/10/27 06:00 [medline]
AID - 000339841 [pii]
AID - 10.1159/000339841 [doi]
PST - ppublish
SO  - Ophthalmic Res. 2012;48 Suppl 1:6-10. doi: 10.1159/000339841. Epub 2012 Aug 21.