PMID- 22913219
OWN - NLM
STAT- MEDLINE
DCOM- 20120906
LR  - 20120823
IS  - 1128-3602 (Print)
IS  - 1128-3602 (Linking)
VI  - 16
IP  - 6
DP  - 2012 Jun
TI  - Significance of bacteriuria and leukocyturia in the outpatients with heart 
      failure.
PG  - 839-44
AB  - AIM: To investigate the relationship between severity of illness and 
      hospitalization with the presence of leukocyturia and bacteriuria in outpatients 
      with heart failure (HF). PATIENTS AND METHODS: Four hundred three patients 
      admitted with the diagnosis of HF to cardiology outpatient clinic were included 
      in this study. According to New York Heart Association (NYHA) classification, the 
      patients were divided into two groups to be group A (decompensated) as stage 3 or 
      4 and group B as stage 1 or 2 (compensated HF). All subjects underwent standard 
      12-lead ECG and echocardiography. In all patients, full blood, biochemical tests 
      as liver and kidney function tests, full urinary analysis (FUA) and thyroid 
      function tests were analyzed. Mid-stream urine for culture was taken for the 
      leukocytes number > or =5 mm3. RESULTS: The mean leukocyte number (MLN) in urine 
      of patients was 16.56 +/- 13.63 in Group A and was 3.74 +/- 5.31 in Group B (p < 
      0.000). The moderately positive correlation was found between the MLN and NHYA 
      class in all patients (r = 0.526; p < 0.000). In receiver operating 
      characteristic (ROC) curve analysis, the optimal cut-off value of leukocytes in 
      urinalysis to predict hospitalization of CHF was > or =5, with 76.1% sensitivity 
      and 75.7% specificity (area under the curve 0.825, 95% confidence interval 0.781 
      to 0.862, p = 0.000). CONCLUSIONS: We found that the numbers of leukocytes in 
      urinalysis of hospitalized patients with HF were significantly higher than 
      non-hospitalized persons. Also, number of leukocyte in urinalysis was positively 
      correlated with NYHA class of HF patients. Namely, leukocyturia may be an 
      indicator of decompensations in HF patients.
FAU - Kucukbayrak, A
AU  - Kucukbayrak A
AD  - Department of Infectious Diseases and Clinical Microbiology, Izzet Baysal Medical 
      Faculty, Bolu, Turkey. abdulbayrak@yahoo.com
FAU - Tas, T
AU  - Tas T
FAU - Kemahli, E
AU  - Kemahli E
FAU - Ayhan, S S
AU  - Ayhan SS
FAU - Ozturk, S
AU  - Ozturk S
FAU - Ozlu, M F
AU  - Ozlu MF
FAU - Erdem, A
AU  - Erdem A
FAU - Yazic, M
AU  - Yazic M
FAU - Akdeniz, H
AU  - Akdeniz H
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
SB  - IM
MH  - Aged
MH  - Bacteriuria/*epidemiology
MH  - Female
MH  - Heart Failure/*complications
MH  - Hospitalization
MH  - Humans
MH  - Leukocyte Count
MH  - Leukocytes/*metabolism
MH  - Male
MH  - Middle Aged
MH  - Outpatients
MH  - ROC Curve
MH  - Urine/*cytology
EDAT- 2012/08/24 06:00
MHDA- 2012/09/07 06:00
CRDT- 2012/08/24 06:00
PHST- 2012/08/24 06:00 [entrez]
PHST- 2012/08/24 06:00 [pubmed]
PHST- 2012/09/07 06:00 [medline]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2012 Jun;16(6):839-44.