PMID- 22913528 OWN - NLM STAT- MEDLINE DCOM- 20131028 LR - 20191210 IS - 1468-3083 (Electronic) IS - 0926-9959 (Linking) VI - 27 IP - 9 DP - 2013 Sep TI - Validation of a clinical evaluation score for irritative dermatitis: SCOREPI. PG - 1138-42 LID - 10.1111/j.1468-3083.2012.04678.x [doi] AB - BACKGROUND: Most dermatological conditions can be evaluated using validate clinical scores, no such tool is available for irritant contact dermatitis (ICD). OBJECTIVE: To create and validate a grid-based ICD severity score. METHODS: Three dermatologists developed the SCOre de REparation de l'EPIderme (SCOREPI) grid. Two studies were conducted to validate the SCOREPI. A cross-sectional study assessed the intra- and inter-observer error associated with using the SCOREPI. Each investigator received 15 min of training on proper use of the SCOREPI. A computer displayed a series of 20 photos of ICD, each of which were repeated three times in a randomized order. The prospective study assessed the correlation between SCOREPI with the severity of clinical symptoms as well as the sensitivity of the score to changes in ICD in response to topical treatment. RESULTS: The SCOREPI took an average of 35 +/- 5 s to be completed and was characterized by an excellent intra-observer and moderate inter-observer reproducibility (intra-class correlation coefficient = 0.93 and 0.74, respectively). Significant divergence was observed between the physicians' assessment of estimated surface (P = 0.04), the presence of erythema (P < 0.0001) and the number of deep cracks (P = 0.0008). In the prospective analysis of patients, SCOREPI was correlated with tightness (r = 0.45; P < 0.0001), pain (r = 0.45; P < 0.0001), burning (r = 0.42; P < 0.0001), and pruritus (r = 0.28; P = 0.0055). SCOREPI decreased considerably during follow-up from 10.45 +/- 4.61 to 4.82 +/- 4.15 (P < 0.0001). CONCLUSION: The SCOREPI is easy to use, sensitive to change, and characterized by high intra- and moderate inter-observer reliability. CI - (c) 2012 The Authors. Journal of the European Academy of Dermatology and Venereology (c) 2012 European Academy of Dermatology and Venereology. FAU - Le Maitre, M AU - Le Maitre M AD - mile-maitre@wanadoo.fr FAU - Crickx, B AU - Crickx B FAU - Lacour, J P AU - Lacour JP FAU - Bagot, M AU - Bagot M FAU - Chevallier, J-M AU - Chevallier JM FAU - Cribier, B AU - Cribier B FAU - Doutre, M-S AU - Doutre MS FAU - Giordano-Labadie, F AU - Giordano-Labadie F FAU - Guillot, B AU - Guillot B FAU - Joly, P AU - Joly P FAU - Schmutz, J-L AU - Schmutz JL FAU - Vabres, P AU - Vabres P FAU - Bensimon, D AU - Bensimon D LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Study DEP - 20120822 PL - England TA - J Eur Acad Dermatol Venereol JT - Journal of the European Academy of Dermatology and Venereology : JEADV JID - 9216037 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Cross-Sectional Studies MH - Dermatitis, Irritant/*diagnosis MH - Female MH - Humans MH - Infant MH - Male MH - Middle Aged MH - Prospective Studies MH - *Severity of Illness Index MH - Young Adult EDAT- 2012/08/24 06:00 MHDA- 2013/10/29 06:00 CRDT- 2012/08/24 06:00 PHST- 2012/08/24 06:00 [entrez] PHST- 2012/08/24 06:00 [pubmed] PHST- 2013/10/29 06:00 [medline] AID - 10.1111/j.1468-3083.2012.04678.x [doi] PST - ppublish SO - J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1138-42. doi: 10.1111/j.1468-3083.2012.04678.x. Epub 2012 Aug 22.