PMID- 22913897 OWN - NLM STAT- MEDLINE DCOM- 20121120 LR - 20221207 IS - 1941-9260 (Electronic) IS - 0032-5481 (Linking) VI - 124 IP - 4 DP - 2012 Jul TI - Diabetes pharmacotherapy in 2012: considerations in medication selection. PG - 84-94 LID - 10.3810/pgm.2012.07.2571 [doi] AB - Diabetes is one of the most costly and burdensome chronic diseases, and its therapy and management have become increasingly complex. The incidence of type 2 diabetes mellitus (T2DM), a multiorgan disorder, is increasing at an epidemic rate in the United States and worldwide. Despite numerous scientific and medical advances, less than half of the population with T2DM has achieved the American Diabetes Association-recommended glycated hemoglobin level goal of < 7%, which is necessary to optimally manage the disease to prevent and minimize complications. There are many patient- and clinician-determined barriers that hinder patients from achieving target blood glucose levels. Therefore, it is imperative for health care professionals who treat patients with T2DM (and those at risk for developing T2DM) to have an enhanced knowledge base of the current pathophysiology, treatment options, and clinical guidelines for T2DM and its related conditions. FAU - Cornell, Susan AU - Cornell S AD - Midwestern University Chicago College of Pharmacy, Downers Grove, IL 60515, USA. scorne@midwestern.edu FAU - Dorsey, Vincent J AU - Dorsey VJ LA - eng PT - Journal Article PT - Review PL - England TA - Postgrad Med JT - Postgraduate medicine JID - 0401147 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) RN - 0 (Hypoglycemic Agents) SB - IM MH - Blood Glucose/metabolism MH - Diabetes Mellitus/*drug therapy/physiopathology/therapy MH - Drug Therapy MH - Drug Therapy, Combination MH - Glycated Hemoglobin/analysis MH - Humans MH - Hypoglycemic Agents/adverse effects/*therapeutic use MH - Incidence MH - Life Style MH - United States/epidemiology EDAT- 2012/08/24 06:00 MHDA- 2012/12/10 06:00 CRDT- 2012/08/24 06:00 PHST- 2012/08/24 06:00 [entrez] PHST- 2012/08/24 06:00 [pubmed] PHST- 2012/12/10 06:00 [medline] AID - 10.3810/pgm.2012.07.2571 [doi] PST - ppublish SO - Postgrad Med. 2012 Jul;124(4):84-94. doi: 10.3810/pgm.2012.07.2571.