PMID- 22917692 OWN - NLM STAT- MEDLINE DCOM- 20131023 LR - 20151119 IS - 1477-0970 (Electronic) IS - 1352-4585 (Linking) VI - 19 IP - 4 DP - 2013 Apr TI - Perceived changes and minimum clinically important difference of the Neurological Fatigue Index for multiple sclerosis (NFI-MS). PG - 502-5 LID - 10.1177/1352458512457840 [doi] AB - The determination of the minimum clinically important difference (MCID) is an important aspect of scale development. The Neurological Fatigue Index for multiple sclerosis (NFI-MS) was administered before and after expected change or stability in fatigue in 208 multiple sclerosis (MS) patients. The overall change scores of the NFI-MS accorded with perceived direction of change; importantly, no change was seen when none was perceived. Using the interval level NFI-MS scores, the largest MCID equated to 2.49 points on the Summary scale, 2.36 points on the Physical scale, 0.84 points on the Cognitive scale, 0.97 on the Diurnal Sleep scale and 1.95 on the Nocturnal Sleep scale. Our conclusion is that the NFI-MS responds as expected to changes in fatigue and has desirably small MCID scores. FAU - Mills, R J AU - Mills RJ AD - Department of Neurology, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK. rjm@crazydiamond.co.uk FAU - Calabresi, M AU - Calabresi M FAU - Tennant, A AU - Tennant A FAU - Young, C A AU - Young CA LA - eng PT - Journal Article DEP - 20120823 PL - England TA - Mult Scler JT - Multiple sclerosis (Houndmills, Basingstoke, England) JID - 9509185 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Fatigue/*etiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Multiple Sclerosis/*complications MH - *Severity of Illness Index MH - Surveys and Questionnaires EDAT- 2012/08/25 06:00 MHDA- 2013/10/24 06:00 CRDT- 2012/08/25 06:00 PHST- 2012/08/25 06:00 [entrez] PHST- 2012/08/25 06:00 [pubmed] PHST- 2013/10/24 06:00 [medline] AID - 1352458512457840 [pii] AID - 10.1177/1352458512457840 [doi] PST - ppublish SO - Mult Scler. 2013 Apr;19(4):502-5. doi: 10.1177/1352458512457840. Epub 2012 Aug 23.