PMID- 22924002 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121002 LR - 20240512 IS - 1178-7007 (Electronic) IS - 1178-7007 (Linking) VI - 5 DP - 2012 TI - Six-minute walk test in non-insulin-dependent diabetes mellitus patients living in Northwest Africa. PG - 227-45 LID - 10.2147/DMSO.S28642 [doi] AB - INTRODUCTION: International recommendations of the exploration of non-insulin-dependent diabetes mellitus (NIDDM) are focused on deficiency and not incapacity. AIMS: (1) To estimate the incapacity of NIDDM patients through the 6-minute walk test (6MWT) data. (2) To determine their 6-minute walk distance (6MWD) influencing factors (3) To compare data of NIDDM patient group (PG; n = 100) with those of two control groups (CG): CG1 (n = 174, healthy nonobese and nonsmoker); CG2 (n = 55, obese nondiabetic free from comorbidities). POPULATION AND METHODS: The anthropometric, socioeconomic, clinical, metabolic, and 6MWT data of 100 NIDDM patients (45 females) were collected. RESULTS: Total sample means +/- standard deviation of age, weight, and height were 54 +/- 8 years, 81 +/- 14 kg, and 1.64 +/- 0.09 m. (1) Measured 6MWD (566 +/- 81 m) was significantly lower than the theoretical 6MWD (90% +/- 12%). The profile of the PG carrying the 6MWT, was as follows: 23% had an abnormal 6MWD; at the end of the 6MWT, 21% and 12% had, respectively, a low heart rate and a high dyspnea (>5/10), and 4% had desaturation during the walk. The estimated "cardiorespiratory and muscular chain" age (68 +/- 16 years) was significantly higher than the chronological age. (2) The factors that significantly influenced the 6MWD (r(2) = 0.58) are included in the following equation: 6MWD (m) = -73.94 x gender (0, male; 1, female) - 3.25 x age (years) + 7.33 x leisure activity score - 35.57 x obesity (0, no; 1, yes) + 32.86 x socioeconomic level (0, low; 1, high) - 27.67 x cigarette use (0, no; 1, yes) + 8.89 x resting oxyhemoglobin saturation - 105.48. (3) Compared to the CGs, the PG had a significantly (P < 0.05) lower 6MWD (100%+9% and 100%+8%, respectively, for the CG1 and CG2). CONCLUSION: NIDDM seems to accelerate the decline of the submaximal aerobic capacity evaluated through the 6MWD. FAU - Latiri, Imed AU - Latiri I AD - Laboratory of Physiology, University of Sousse, Sousse, Tunisia. FAU - Elbey, Rihab AU - Elbey R FAU - Hcini, Kamel AU - Hcini K FAU - Zaoui, Afif AU - Zaoui A FAU - Charfeddine, Bessam AU - Charfeddine B FAU - Maarouf, Mohamed Ridha AU - Maarouf MR FAU - Tabka, Zouhair AU - Tabka Z FAU - Zbidi, Abdelkrim AU - Zbidi A FAU - Ben Saad, Helmi AU - Ben Saad H LA - eng PT - Journal Article DEP - 20120807 PL - New Zealand TA - Diabetes Metab Syndr Obes JT - Diabetes, metabolic syndrome and obesity : targets and therapy JID - 101515585 PMC - PMC3422904 OTO - NOTNLM OT - 6-minute walk test OT - functional incapacity OT - non-insulin-dependent diabetes mellitus OT - physical activity EDAT- 2012/08/28 06:00 MHDA- 2012/08/28 06:01 PMCR- 2012/08/07 CRDT- 2012/08/28 06:00 PHST- 2012/08/28 06:00 [entrez] PHST- 2012/08/28 06:00 [pubmed] PHST- 2012/08/28 06:01 [medline] PHST- 2012/08/07 00:00 [pmc-release] AID - dmso-5-227 [pii] AID - 10.2147/DMSO.S28642 [doi] PST - ppublish SO - Diabetes Metab Syndr Obes. 2012;5:227-45. doi: 10.2147/DMSO.S28642. Epub 2012 Aug 7.