PMID- 22925391
OWN - NLM
STAT- MEDLINE
DCOM- 20140324
LR  - 20130129
IS  - 1751-7893 (Electronic)
IS  - 1751-7885 (Linking)
VI  - 7
IP  - 1
DP  - 2013 Feb
TI  - Childhood trauma and premorbid adjustment among individuals at clinical high risk 
      for psychosis and normal control subjects.
PG  - 51-7
LID - 10.1111/j.1751-7893.2012.00391.x [doi]
AB  - AIM: Traumatic childhood experiences are associated with psychotic illness and 
      are frequently reported in patients at clinical high risk (CHR) for psychosis. 
      Moreover, deteriorating premorbid functioning from childhood, and through 
      adolescence, is related to greater severity of overall symptomatology and poorer 
      outcomes in patients with psychosis. We studied the prevalence of traumatic 
      childhood experiences and premorbid adjustment and their association with each 
      other in patients at CHR for psychosis and normal control subjects (NCSs). 
      METHODS: A total of 20 CHR patients for psychosis and 30 NCSs aged 14 to 35 
      participated in the present study. The CHR patients were identified as prodromal 
      to psychosis using the Structured Interview for Prodromal Syndromes/Scale of 
      Prodromal Symptoms. Premorbid adjustment was assessed by using the premorbid 
      adjustment scale (PAS), and self-reported childhood trauma was assessed with the 
      Trauma and Distress Scale (TADS). RESULTS: In CHR patients, TADS and PAS scores 
      were higher than in NCSs. In CHR patients, TADS correlated significantly with the 
      PAS general section and observably, but not significantly, with adolescence and 
      adulthood sections. CONCLUSION: CHR patients reported more childhood trauma 
      experiences and poorer premorbid adjustment than NCSs. In CHR patients, traumatic 
      childhood experiences are associated with poor general premorbid adjustment.
CI  - (c) 2012 Wiley Publishing Asia Pty Ltd.
FAU - Tikka, Maria
AU  - Tikka M
AD  - Department of Psychiatry, University of Turku, Turku, Finland. maria.tikka@utu.fi
FAU - Luutonen, Sinikka
AU  - Luutonen S
FAU - Ilonen, Tuula
AU  - Ilonen T
FAU - Tuominen, Lauri
AU  - Tuominen L
FAU - Kotimaki, Mika
AU  - Kotimaki M
FAU - Hankala, Juha
AU  - Hankala J
FAU - Salokangas, Raimo K R
AU  - Salokangas RK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120826
PL  - Australia
TA  - Early Interv Psychiatry
JT  - Early intervention in psychiatry
JID - 101320027
SB  - IM
CIN - Early Interv Psychiatry. 2013 Feb;7(1):1-4. PMID: 23356889
MH  - *Adaptation, Psychological
MH  - Adolescent
MH  - Adult
MH  - Adult Survivors of Child Abuse/*psychology
MH  - Case-Control Studies
MH  - Female
MH  - Finland
MH  - Humans
MH  - Male
MH  - Psychiatric Status Rating Scales
MH  - Psychotic Disorders/diagnosis/*psychology
MH  - Risk Factors
MH  - Self Report
MH  - Severity of Illness Index
EDAT- 2012/08/29 06:00
MHDA- 2014/03/25 06:00
CRDT- 2012/08/29 06:00
PHST- 2011/08/09 00:00 [received]
PHST- 2012/06/07 00:00 [accepted]
PHST- 2012/08/29 06:00 [entrez]
PHST- 2012/08/29 06:00 [pubmed]
PHST- 2014/03/25 06:00 [medline]
AID - 10.1111/j.1751-7893.2012.00391.x [doi]
PST - ppublish
SO  - Early Interv Psychiatry. 2013 Feb;7(1):51-7. doi: 
      10.1111/j.1751-7893.2012.00391.x. Epub 2012 Aug 26.