PMID- 22928605
OWN - NLM
STAT- MEDLINE
DCOM- 20130206
LR  - 20211021
IS  - 1471-2164 (Electronic)
IS  - 1471-2164 (Linking)
VI  - 13
DP  - 2012 Aug 28
TI  - Chromosomal differences between European and North American Atlantic salmon 
      discovered by linkage mapping and supported by fluorescence in situ hybridization 
      analysis.
PG  - 432
LID - 10.1186/1471-2164-13-432 [doi]
AB  - BACKGROUND: Geographical isolation has generated a distinct difference between 
      Atlantic salmon of European and North American Atlantic origin. The European 
      Atlantic salmon generally has 29 pairs of chromosomes and 74 chromosome arms 
      whereas it has been reported that the North American Atlantic salmon has 27 
      chromosome pairs and an NF of 72. In order to predict the major chromosomal 
      rearrangements causing these differences, we constructed a dense linkage map for 
      Atlantic salmon of North American origin and compared it with the well-developed 
      map for European Atlantic salmon. RESULTS: The presented male and female genetic 
      maps for the North American subspecies of Atlantic salmon, contains 3,662 SNPs 
      located on 27 linkage groups. The total lengths of the female and male linkage 
      maps were 2,153 cM and 968 cM respectively, with males characteristically showing 
      recombination only at the telomeres. We compared these maps with recently 
      published SNP maps from European Atlantic salmon, and predicted three chromosomal 
      reorganization events that we then tested using fluorescence in situ 
      hybridization (FISH) analysis. The proposed rearrangements, which define the 
      differences in the karyotypes of the North American Atlantic salmon relative to 
      the European Atlantic salmon, include the translocation of the p arm of ssa01 to 
      ssa23 and polymorphic fusions: ssa26 with ssa28, and ssa08 with ssa29. 
      CONCLUSIONS: This study identified major chromosomal differences between European 
      and North American Atlantic salmon. However, while gross structural differences 
      were significant, the order of genetic markers at the fine-resolution scale was 
      remarkably conserved. This is a good indication that information from the 
      International Cooperation to Sequence the Atlantic salmon Genome, which is 
      sequencing a European Atlantic salmon, can be transferred to Atlantic salmon from 
      North America.
FAU - Brenna-Hansen, Silje
AU  - Brenna-Hansen S
AD  - Centre of Integrative Genetics and Department of Animal and Aquacultural 
      Sciences, Norwegian University of Life Sciences, P,O, Box 5003,, 1430, As, 
      Norway.
FAU - Li, Jieying
AU  - Li J
FAU - Kent, Matthew P
AU  - Kent MP
FAU - Boulding, Elizabeth G
AU  - Boulding EG
FAU - Dominik, Sonja
AU  - Dominik S
FAU - Davidson, William S
AU  - Davidson WS
FAU - Lien, Sigbjorn
AU  - Lien S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120828
PL  - England
TA  - BMC Genomics
JT  - BMC genomics
JID - 100965258
SB  - IM
MH  - Animals
MH  - Chromosome Mapping/*methods
MH  - Chromosomes/*genetics
MH  - Female
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Male
MH  - Salmon/*genetics
PMC - PMC3495403
EDAT- 2012/08/30 06:00
MHDA- 2013/02/07 06:00
PMCR- 2012/08/28
CRDT- 2012/08/30 06:00
PHST- 2012/02/11 00:00 [received]
PHST- 2012/08/09 00:00 [accepted]
PHST- 2012/08/30 06:00 [entrez]
PHST- 2012/08/30 06:00 [pubmed]
PHST- 2013/02/07 06:00 [medline]
PHST- 2012/08/28 00:00 [pmc-release]
AID - 1471-2164-13-432 [pii]
AID - 10.1186/1471-2164-13-432 [doi]
PST - epublish
SO  - BMC Genomics. 2012 Aug 28;13:432. doi: 10.1186/1471-2164-13-432.