PMID- 22930206
OWN - NLM
STAT- MEDLINE
DCOM- 20130408
LR  - 20221207
IS  - 1477-0962 (Electronic)
IS  - 0961-2033 (Linking)
VI  - 21
IP  - 13
DP  - 2012 Nov
TI  - Pure cutaneous lupus erythematosus in a population of African descent in French 
      Guiana: a retrospective population-based description.
PG  - 1467-71
LID - 10.1177/0961203312458167 [doi]
AB  - The objective of this study was to examine the characteristics of cutaneous lupus 
      erythematosus, excluding systemic lupus erythematosus (SLE), in patients of 
      African descent. Indeed, since the description of subacute cutaneous lupus 
      erythematosus (SCLE), which had been included in chronic cutaneous lupus 
      erythematosus (CCLE), there has been no description of the disease in black 
      patients. In 2000, we performed a retrospective epidemiological study by querying 
      multiple sources to identify all patients with lupus in French Guiana--a part of 
      France in South America having western living conditions, free healthcare and 
      157,000 inhabitants, most of whom are of African origin. We found 45 patients 
      with pure cutaneous lupus, which included CCLE (mostly discoid), SCLE and bullous 
      lupus. The disease characteristics of these patients exhibited few differences 
      compared with those of the Caucasian patients cited in the literature. However, 
      the age of onset for our patients of African descent was younger than that of 
      Caucasian patients. In contrast to the race-related differences reported for SLE, 
      we found no major differences in terms of demographic, clinical and biological 
      presentation between this cohort of pure cutaneous lupus erythematosus patients 
      of African origin and Caucasian patients with similar forms of lupus.
FAU - Deligny, C
AU  - Deligny C
AD  - Centre regional de competences "maladies autoimmunes rares", Centre hospitalier 
      la Meynard, Martinique, France. christophe.deligny@chu-fortdefrance.fr
FAU - Marie, D Sainte
AU  - Marie DS
FAU - Clyti, E
AU  - Clyti E
FAU - Arfi, S
AU  - Arfi S
FAU - Couppie, P
AU  - Couppie P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20120828
PL  - England
TA  - Lupus
JT  - Lupus
JID - 9204265
RN  - 0 (Antibodies, Antinuclear)
RN  - 0 (Biomarkers)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age of Onset
MH  - Antibodies, Antinuclear/blood
MH  - Biomarkers/blood
MH  - *Black People
MH  - Child
MH  - Female
MH  - French Guiana/epidemiology
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/blood/diagnosis/*ethnology/immunology
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Skin/pathology
MH  - White People
MH  - Young Adult
EDAT- 2012/08/30 06:00
MHDA- 2013/04/09 06:00
CRDT- 2012/08/30 06:00
PHST- 2012/08/30 06:00 [entrez]
PHST- 2012/08/30 06:00 [pubmed]
PHST- 2013/04/09 06:00 [medline]
AID - 0961203312458167 [pii]
AID - 10.1177/0961203312458167 [doi]
PST - ppublish
SO  - Lupus. 2012 Nov;21(13):1467-71. doi: 10.1177/0961203312458167. Epub 2012 Aug 28.