PMID- 22934408
OWN - NLM
STAT- MEDLINE
DCOM- 20130905
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 5
DP  - 2012 May
TI  - [Determination of virginiamycin M1 and S1 residues in livestock and poultry 
      products by liquid chromatography-tandem mass spectrometry].
PG  - 463-7
AB  - A liquid chromatography-tandem mass spectrometry method was established for the 
      determination of virginiamycin M1 and S1 residues in livestock and poultry 
      products. The sample was extracted by methanol-acetonitrile solution (1:1, v/v). 
      The supernatant was diluted with 0.01 mol/L ammonium dihydrogen phosphate 
      solution, then purified and concentrated on an Oasis HLB cartridge. The 
      separation of virginiamycin M1 and S1 was performed on a Luna C18 column with the 
      mobile phases acetonitrile and 5 mmol/L ammonium acetate aqueous solution 
      (containing 0.1% (v/v) formic acid) in a gradient elution mode. The 
      identification and quantification of the drugs were carried out by positive 
      electrospray ionization (ESI + ) in the multiple reaction monitoring (MRM) mode 
      using external standard method. The calibration curves showed good linearity in 
      the range of 0.15-10.0 microg/L with correlation coefficients (r2) above 0. 999. 
      The limits of quantities (LOQs) were both 0.25 microg/kg. The average recoveries 
      of the two drugs spiked at 0.25, 0.5 and 2.5 microg/kg levels in different 
      matrices were between 71.2% and 98.4%, and the relative standard deviations 
      (RSDs) were between 3.6% and 15.4%. The method is simple, rapid, sensitive and 
      accurate. It is suitable for the confirmation and quantification of virginiamycin 
      M1 and S1 residues in livestock and poultry products.
FAU - Qiu, Yuanjin
AU  - Qiu Y
AD  - Fujian Entry-Exit Inspection and Quarantine Bureau, Fuzhou 350001, China. 
      yjqiuzju@163.com
FAU - Yang, Fang
AU  - Yang F
FAU - Liu, Zhengcai
AU  - Liu Z
FAU - Lin, Yonghui
AU  - Lin Y
FAU - Liu, Suzhen
AU  - Liu S
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Streptogramin Group B)
RN  - 11006-76-1 (Virginiamycin)
RN  - 8W4UOL59AZ (Streptogramin A)
RN  - J91D5GN5AT (virginiamycin factor S1)
SB  - IM
MH  - Animals
MH  - Chromatography, Liquid/*methods
MH  - Drug Residues/analysis
MH  - Food Contamination/analysis
MH  - Livestock
MH  - Meat Products/*analysis
MH  - Poultry
MH  - Streptogramin A/*analysis
MH  - Streptogramin Group B/*analysis
MH  - Tandem Mass Spectrometry/*methods
MH  - Virginiamycin/*analysis
EDAT- 2012/09/01 06:00
MHDA- 2013/09/06 06:00
CRDT- 2012/09/01 06:00
PHST- 2012/09/01 06:00 [entrez]
PHST- 2012/09/01 06:00 [pubmed]
PHST- 2013/09/06 06:00 [medline]
AID - 10.3724/sp.j.1123.2012.01020 [doi]
PST - ppublish
SO  - Se Pu. 2012 May;30(5):463-7. doi: 10.3724/sp.j.1123.2012.01020.