PMID- 22934411
OWN - NLM
STAT- MEDLINE
DCOM- 20130905
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 5
DP  - 2012 May
TI  - [Determination of 21 fragrance allergens in toys by gas chromatography-ion trap 
      mass spectrometry].
PG  - 480-6
AB  - A method of gas chromatography-ion trap mass spectrometry (GC-IT-MS) was 
      developed for the determination of 21 fragrance allergens in sticker toys, plush 
      toys and plastic toys. The experimental conditions, such as sample pretreatment 
      conditions, and the analytical conditions of GC-IT-MS, were optimized. The 
      sticker toy samples and plush toy samples were extracted with acetone by 
      ultrasonic wave, and the extracts were separated on an Agilent HP-1 MS column (50 
      m x 0.2 mm x 0.5 microm), then determined by IT-MS and quantified by external 
      standard method. The plastic toy samples were extracted by the 
      dissolution-precipitation approach, cleaned up with an Envi-carb solid phase 
      extraction column and concentrated by rotary evaporation and nitrogen blowing, 
      then determined by GC-IT-MS and quantified by external standard method. The 
      calibration curves showed good linearity in the range of 0.002-50 mg/L with the 
      correlation coefficients greater than 0.996 8. The limits of quantification (LOQ, 
      S/N > 10) were 0.02-40 mg/kg. The average recoveries of the target compounds 
      spiked in the sample at three concentration levels were in the range of 
      82.2%-110.8% with the relative standard deviations (RSDs) of 0.6%-10.5%. These 
      results show that this method is accurate and sensitive for the qualitative and 
      quantitative determination of the 21 fragrance allergens in the 3 types of toys.
FAU - Lu, Qing
AU  - Lu Q
AD  - Institute of Industrial Product Inspection, Chinese Academy of Inspection and 
      Quarantine, Beijing 100123, China.
FAU - Zang, Qing
AU  - Zang Q
FAU - Bai, Hua
AU  - Bai H
FAU - Li, Haiyu
AU  - Li H
FAU - Kang, Suyuan
AU  - Kang S
FAU - Wang, Chao
AU  - Wang C
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Allergens)
RN  - 0 (Perfume)
SB  - IM
MH  - Allergens/*analysis/*isolation & purification
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Perfume/*analysis/*isolation & purification
MH  - Play and Playthings
EDAT- 2012/09/01 06:00
MHDA- 2013/09/06 06:00
CRDT- 2012/09/01 06:00
PHST- 2012/09/01 06:00 [entrez]
PHST- 2012/09/01 06:00 [pubmed]
PHST- 2013/09/06 06:00 [medline]
AID - 10.3724/sp.j.1123.2011.12005 [doi]
PST - ppublish
SO  - Se Pu. 2012 May;30(5):480-6. doi: 10.3724/sp.j.1123.2011.12005.