PMID- 22934418
OWN - NLM
STAT- MEDLINE
DCOM- 20130905
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 5
DP  - 2012 May
TI  - [Simultaneous determination of 6 forbidden colorants in cosmetics by high 
      performance liquid chromatography-tandem mass spectrometry].
PG  - 527-32
AB  - A method of high performance liquid chromatography-tandem mass spectrometry 
      (HPLC-MS/MS) has been established for the simultaneous determination of six 
      forbidden colorants including Sudan IV, Acid Violet 49, Sudan Blue 2, Solvent Red 
      49, Basic Violet 1 and Pigment Orange 5 in cream and powdery matrix cosmetics. 
      The samples were extracted with ethanol-acetonitrile (3:2, v/v) solution by 
      ultrasonic technique for 20 min, then centrifuged for purification and enriched 
      by nitrogen blowing sequentially. The analytes were isolated on a Luna C18 column 
      (150 mm x 2.1 mm, 5 microm) by gradient elution with methanol and 10 mmol/L 
      ammonium acetate as the mobile phases, and detected by MS/MS in the multiple 
      reaction monitoring (MRM) mode. The qualitative analysis was based on the 
      retention time and the relative abundance ratio of the characteristic ions, and 
      the quantitative analysis on calibration curve method. The results showed that 
      the limits of quantification (LOQ, S/N= 10) of the six colorants ranged from 0.1 
      to 10 microg/kg and the average recoveries were from 86.67% to 98.22% with the 
      relative standard deviations (RSDs) from 4.01% to 7.01%. The method is simple and 
      rapid with high sensitivity and good reproducibility, and suitable for the 
      determination of the six forbidden colorants in cosmetics.
FAU - Lin, Weixuan
AU  - Lin W
AD  - Liaoning Entry-Exit Inspection and Quarantine Bureau, Dalian 116001, China. 
      dlciqlwx@sina.com
FAU - Sun, Xingquan
AU  - Sun X
FAU - Zhao, Xuerong
AU  - Zhao X
FAU - Xu, Wei
AU  - Xu W
FAU - Guo, Guiyuan
AU  - Guo G
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Azo Compounds)
RN  - 0 (Benzenesulfonates)
RN  - 0 (Coloring Agents)
RN  - 0 (Cosmetics)
RN  - 0 (Rosaniline Dyes)
RN  - 1694-09-3 (Acid Violet 6B)
RN  - H2G44K8M7S (Basic Violet 1)
RN  - I35E9QU96C (Scarlet Red)
SB  - IM
MH  - Azo Compounds/analysis
MH  - Benzenesulfonates/analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Coloring Agents/*analysis
MH  - Cosmetics/*chemistry
MH  - Humans
MH  - Rosaniline Dyes/analysis
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2012/09/01 06:00
MHDA- 2013/09/06 06:00
CRDT- 2012/09/01 06:00
PHST- 2012/09/01 06:00 [entrez]
PHST- 2012/09/01 06:00 [pubmed]
PHST- 2013/09/06 06:00 [medline]
AID - 10.3724/sp.j.1123.2011.11049 [doi]
PST - ppublish
SO  - Se Pu. 2012 May;30(5):527-32. doi: 10.3724/sp.j.1123.2011.11049.