PMID- 22935202
OWN - NLM
STAT- MEDLINE
DCOM- 20130624
LR  - 20131121
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 109
IP  - 9
DP  - 2013 May
TI  - Associations of plasma phospholipid fatty acids with plasma homocysteine in 
      Chinese vegetarians.
PG  - 1688-94
LID - 10.1017/S000711451200356X [doi]
AB  - The association of plasma phospholipid (PL) fatty acid composition with plasma 
      homocysteine (Hcy) in Chinese vegetarians is not understood. The main aim of the 
      present study was to investigate the plasma PL fatty acid status, and its 
      association with plasma Hcy in Chinese vegetarians and omnivores. A total of 103 
      male vegetarians and 128 male omnivores were recruited in Linyin Temple, 
      Hangzhou. Plasma Hcy and PL fatty acid concentrations were determined by standard 
      methods. Compared with omnivores, plasma PL n-3 PUFA (P< 0.001), 22 : 6n-3 (P< 
      0.001), 22 : 5n-6 (P= 0.021), 22 : 2n-6 (P< 0.001) and SFA (P= 0.017) were 
      significantly lower, while plasma PL n-6 PUFA (P= 0.007) and total PUFA (P< 
      0.001) were significantly higher in vegetarians. The prevalence of 
      hyperhomocysteinaemia (HHcy) in vegetarians (26.47 %) was significantly higher 
      than that in omnivores (13.28 %). In vegetarians, plasma PL 22 : 6n-3 (r - 0.257, 
      P= 0.046) was significantly negatively associated with plasma Hcy. In omnivores, 
      plasma PL 18 : 1n-7 (r 0.237, P= 0.030) was significantly positively associated 
      with plasma Hcy. Plasma PL 22 : 6n-3 (r - 0.217, P= 0.048) was negatively 
      associated with plasma Hcy in omnivores. Plasma PL SFA were positively associated 
      with the prevalence of HHcy. It would seem appropriate for vegetarians to 
      increase their dietary n-3 PUFA and decrease dietary SFA, and thus reduce the 
      risk of HHcy.
FAU - Huang, Tao
AU  - Huang T
AD  - Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang 
      Road, Hangzhou, People's Republic of China.
FAU - Yu, Xiaomei
AU  - Yu X
FAU - Shou, Tianxing
AU  - Shou T
FAU - Wahlqvist, Mark L
AU  - Wahlqvist ML
FAU - Li, Duo
AU  - Li D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120831
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Fatty Acids)
RN  - 0 (Phospholipids)
RN  - 0LVT1QZ0BA (Homocysteine)
SB  - IM
MH  - Adult
MH  - China
MH  - *Diet, Vegetarian
MH  - Fatty Acids/*blood
MH  - Female
MH  - Homocysteine/*blood
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Phospholipids/*blood/chemistry
EDAT- 2012/09/01 06:00
MHDA- 2013/06/26 06:00
CRDT- 2012/09/01 06:00
PHST- 2012/09/01 06:00 [entrez]
PHST- 2012/09/01 06:00 [pubmed]
PHST- 2013/06/26 06:00 [medline]
AID - S000711451200356X [pii]
AID - 10.1017/S000711451200356X [doi]
PST - ppublish
SO  - Br J Nutr. 2013 May;109(9):1688-94. doi: 10.1017/S000711451200356X. Epub 2012 Aug 
      31.