PMID- 22939131
OWN - NLM
STAT- MEDLINE
DCOM- 20130117
LR  - 20131121
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 98
DP  - 2012 Aug 30
TI  - Detection of trace levels of lead in aqueous liquids using extractive 
      electrospray ionization tandem mass spectrometry.
PG  - 79-85
LID - 10.1016/j.talanta.2012.06.048 [doi]
AB  - A sensitive approach, based on semi-quantitative measurement of the 
      characteristic fragments in multi-stage extractive electrospray ionization mass 
      spectrometry (EESI-MS(n)), was developed for fast detection of trace levels of 
      lead in aqueous liquids including mineral water, lake water, tap water, energy 
      drinks, soft drinks, beer, orange juice, and tea. A disodium 
      ethylene-diamine-tetraacetic acid (EDTA) aqueous solution was electrosprayed to 
      produce negatively charged primary ions which then intersected the neutral sample 
      plume to generate anions of EDTA-Pb(II) complexes. The charged EDTA-Pb(II) 
      complexes were characterized with multistage collision induced dissociation (CID) 
      experiments. The limit of detection (LOD) using EESI-MS(3) was estimated to be at 
      the level of 10(-13)g/mL for directly detecting lead in many of these samples. 
      The linear dynamic range was higher than 2 orders of magnitude. A single sample 
      analysis could be completed within 2 min with reasonable semi-quantitative 
      performance, e.g., relative standard deviations (RSDs) for deionized water were 
      4.6-7.6% during 5 experimental runs (each of them had 10 repeated measurements). 
      Coca-cola and Huiyuan orange juice, representative beverage samples with complex 
      matrices, generated recovery rates of 91.5% and 129%, respectively. Our 
      experimental data demonstrated that EESI-MS is a useful tool for the fast 
      detection of lead in various solutions, and EESI-MS showed promises for fast 
      screening of lead-contaminated aqueous liquid samples.
CI  - Copyright (c) 2012 Elsevier B.V. All rights reserved.
FAU - Liu, Chunxiao
AU  - Liu C
AD  - State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research 
      Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 
      100085, PR China.
FAU - Zhang, Xinglei
AU  - Zhang X
FAU - Xiao, Saijin
AU  - Xiao S
FAU - Jia, Bin
AU  - Jia B
FAU - Cui, Shasha
AU  - Cui S
FAU - Shi, Jianbo
AU  - Shi J
FAU - Xu, Ning
AU  - Xu N
FAU - Xie, Xi
AU  - Xie X
FAU - Gu, Haiwei
AU  - Gu H
FAU - Chen, Huanwen
AU  - Chen H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120626
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Cations, Divalent)
RN  - 0 (Coordination Complexes)
RN  - 0 (Mineral Waters)
RN  - 0 (Tea)
RN  - 0 (Water Pollutants, Chemical)
RN  - 2P299V784P (Lead)
RN  - 9G34HU7RV0 (Edetic Acid)
SB  - IM
MH  - Beer/analysis
MH  - Carbonated Beverages/analysis
MH  - Cations, Divalent
MH  - Citrus sinensis/chemistry
MH  - Coordination Complexes/chemistry
MH  - Edetic Acid/chemistry
MH  - Lead/*analysis
MH  - Limit of Detection
MH  - Mineral Waters/analysis
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - Tandem Mass Spectrometry
MH  - Tea/chemistry
MH  - Water Pollutants, Chemical/*analysis
EDAT- 2012/09/04 06:00
MHDA- 2013/01/18 06:00
CRDT- 2012/09/04 06:00
PHST- 2012/03/22 00:00 [received]
PHST- 2012/06/14 00:00 [revised]
PHST- 2012/06/20 00:00 [accepted]
PHST- 2012/09/04 06:00 [entrez]
PHST- 2012/09/04 06:00 [pubmed]
PHST- 2013/01/18 06:00 [medline]
AID - S0039-9140(12)00515-2 [pii]
AID - 10.1016/j.talanta.2012.06.048 [doi]
PST - ppublish
SO  - Talanta. 2012 Aug 30;98:79-85. doi: 10.1016/j.talanta.2012.06.048. Epub 2012 Jun 
      26.