PMID- 229478 OWN - NLM STAT- MEDLINE DCOM- 19800215 LR - 20200303 IS - 0032-5791 (Print) IS - 0032-5791 (Linking) VI - 58 IP - 3 DP - 1979 May TI - Development of gluconeogenic, glycolytic, and pentose-shunt enzymes in the chicken kidney. PG - 663-7 AB - The activities of the key gluconeogenic, glycolytic, and pentose-shunt enzymes in chicken kidney were determined starting from 8 days before to 58 days after hatching. The activities of pyruvate carboxylase (PC), mitochondrial and cytosolic phosphoenolypruvate carboxykinase (PEPCK), fructose-1,6-diphosphatase (FDPase) and glucose-6-phosphatase (G6Pase) were low in the embryonic tissue but increased towards the time of hatching. After hatching, the activities of PC, mitochondrial PEPCK, and G6Pase continued to increase, but those of FDPase and cytosolic PEPCK decreased. Relatively little change in these activities was observed in chickens over 24 days old. The activities of hexokinase (HK), phosphofructokinase (PFK), pyruvate kinase (PK), and lactate dehydrogenase (LDH) increased during embryonic growth. After hatching, HK activity continued to increase and then decrease, whereas PFK appeared to decrease and then increase to prehatch levels in 28-day-old birds. LDH activity continued to increase until 8 days after hatching and remained constant thereafter. No definite pattern was discernible in the case of PK. As for the pentose-shunt enzymes, there was no significant change in glucose-6-phosphate dehydrogenase activity (G6PDH), but the activity of 6-phosphogluconate dehydrogenase (6PGDH) increased until the chickens were 14 days old and then remained relatively constant. FAU - Shen, C S AU - Shen CS FAU - Mistry, S P AU - Mistry SP LA - eng PT - Journal Article PL - England TA - Poult Sci JT - Poultry science JID - 0401150 RN - 0 (Pentosephosphates) RN - EC 1.1.1.27 (L-Lactate Dehydrogenase) RN - EC 1.1.1.43 (Phosphogluconate Dehydrogenase) RN - EC 1.1.1.49 (Glucosephosphate Dehydrogenase) RN - EC 2.7.1.1 (Hexokinase) RN - EC 2.7.1.11 (Phosphofructokinase-1) RN - EC 2.7.1.40 (Pyruvate Kinase) RN - EC 3.1.3.11 (Fructose-Bisphosphatase) RN - EC 4.1.1.32 (Phosphoenolpyruvate Carboxykinase (GTP)) SB - IM MH - Animals MH - Chickens/*metabolism MH - Female MH - Fructose-Bisphosphatase/metabolism MH - *Gluconeogenesis MH - Glucosephosphate Dehydrogenase/metabolism MH - *Glycolysis MH - Hexokinase/metabolism MH - Kidney/*enzymology MH - L-Lactate Dehydrogenase/metabolism MH - Pentosephosphates/*metabolism MH - Phosphoenolpyruvate Carboxykinase (GTP)/metabolism MH - Phosphofructokinase-1/metabolism MH - Phosphogluconate Dehydrogenase/metabolism MH - Pyruvate Kinase/metabolism EDAT- 1979/05/01 00:00 MHDA- 1979/05/01 00:01 CRDT- 1979/05/01 00:00 PHST- 1979/05/01 00:00 [pubmed] PHST- 1979/05/01 00:01 [medline] PHST- 1979/05/01 00:00 [entrez] AID - S0032-5791(19)34731-5 [pii] AID - 10.3382/ps.0580663 [doi] PST - ppublish SO - Poult Sci. 1979 May;58(3):663-7. doi: 10.3382/ps.0580663.