PMID- 22950546
OWN - NLM
STAT- MEDLINE
DCOM- 20130627
LR  - 20231106
IS  - 1745-6215 (Electronic)
IS  - 1745-6215 (Linking)
VI  - 13
DP  - 2012 Sep 6
TI  - Treatment of adolescents with depression: the effect of transference 
      interventions in a randomized controlled study of dynamic psychotherapy.
PG  - 159
LID - 10.1186/1745-6215-13-159 [doi]
AB  - BACKGROUND: Depression in adolescents seems to be a growing problem that causes 
      mental suffering and prevents young people from joining the workforce. There is 
      also a high risk of relapse during adult life. There is emerging evidence for the 
      effect of psychodynamic psychotherapy in adolescents. In-session relational 
      intervention (that is, transference intervention) is a key component of 
      psychodynamic psychotherapy. However, whether depressed adolescents profit most 
      from psychodynamic psychotherapy with or without transference interventions has 
      not been stated. OBJECT: The effect of transference interventions in depressed 
      adolescents and the moderator moderating effect of quality of object relations, 
      personality disorder and gender will be explored. METHODS AND STUDY DESIGN: The 
      First Experimental Study of Transference Work-In Teenagers (FEST-IT) will be a 
      randomized clinical trial with a dismantling design. The study is aimed to 
      explore the effects of transference work in psychodynamic psychotherapy for 
      adolescents with depression. One hundred patients ages 16 to 18 years old will be 
      randomized to one of two treatment groups, in both of which general psychodynamic 
      techniques will be used. The patients will be treated over 28 weeks with either a 
      moderate level of transference intervention or no transference intervention. 
      Follow-up will be at 1 year after treatment termination. The outcome measures 
      will be the Psychodynamic Functioning Scales (PFS), Inventory of Interpersonal 
      Problems-Circumplex Version (IIP-C), Global Assessment of Functioning (GAF), and 
      the total mean score of Symptom Checklist-90 (Global Severity Index; GSI), Beck 
      Depression Inventory (BDI), and Montgomery Asberg Rating Scale (MADRS). The 
      quality of adolescents' relationships will be a central focus of the study, and 
      the Adolescent Relationship Scales (ARS) and Differentiation-Relatedness Scale 
      (DRS) will also be used. Change will be assessed using linear-mixed models. 
      Gender personality disorder (PD) and quality of object relations (QOR) will be 
      the preselected putative moderators. DISCUSSION: The object of this clinical 
      trial is to explore the effect of transference interventions in psychodynamic 
      psychotherapy in adolescents with a major depressive disorder. Using a randomized 
      and dismantling design, we hope that the study will add more specific knowledge 
      to the evidence base. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: 
      NCT01531101First Experimental Study of Transference work Work-In Teenagers 
      (FEST-IT).
FAU - Ulberg, Randi
AU  - Ulberg R
AD  - Institute of Clinical Medicine, Department of Psychiatry, University of Oslo, 
      Vinderen, PO Box 85 N-0319, Oslo, Norway. Randi.Ulberg@medisin.uio.no
FAU - Hersoug, Anne Grete
AU  - Hersoug AG
FAU - Hoglend, Per
AU  - Hoglend P
LA  - eng
SI  - ClinicalTrials.gov/NCT01531101
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20120906
PL  - England
TA  - Trials
JT  - Trials
JID - 101263253
SB  - IM
MH  - Adolescent
MH  - Age Factors
MH  - Checklist
MH  - Clinical Protocols
MH  - Depressive Disorder, Major/diagnosis/psychology/*therapy
MH  - Female
MH  - Gender Identity
MH  - Humans
MH  - Male
MH  - Object Attachment
MH  - Personality Disorders/psychology
MH  - Predictive Value of Tests
MH  - Psychiatric Status Rating Scales
MH  - *Psychology, Adolescent
MH  - Psychotherapy/*methods
MH  - *Research Design
MH  - Sex Factors
MH  - Time Factors
MH  - *Transference, Psychology
MH  - Treatment Outcome
MH  - United Kingdom
PMC - PMC3545957
EDAT- 2012/09/07 06:00
MHDA- 2013/06/29 06:00
PMCR- 2012/09/06
CRDT- 2012/09/07 06:00
PHST- 2012/02/10 00:00 [received]
PHST- 2012/07/31 00:00 [accepted]
PHST- 2012/09/07 06:00 [entrez]
PHST- 2012/09/07 06:00 [pubmed]
PHST- 2013/06/29 06:00 [medline]
PHST- 2012/09/06 00:00 [pmc-release]
AID - 1745-6215-13-159 [pii]
AID - 10.1186/1745-6215-13-159 [doi]
PST - epublish
SO  - Trials. 2012 Sep 6;13:159. doi: 10.1186/1745-6215-13-159.