PMID- 2295150
OWN - NLM
STAT- MEDLINE
DCOM- 19900220
LR  - 20071115
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 81
IP  - 1 Suppl
DP  - 1990 Jan
TI  - Evaluation of severity of heart failure using ventilatory gas analysis.
PG  - II31-7
AB  - To evaluate the severity of heart failure, cardiopulmonary exercise testing was 
      performed in 99 normal subjects and in 382 patients with cardiac disease. 
      Anaerobic threshold, peak oxygen uptake, and the ratio of increase in oxygen 
      uptake to work-rate increment were determined by ventilatory and gas exchange 
      measurements as indexes for assessing the severity of heart failure. Anaerobic 
      threshold and peak oxygen uptake declined with age, and males showed higher 
      values than females in both indexes. Anaerobic threshold, as the percentage of 
      predicted value for age, sex, and body weight, decreased as New York Heart 
      Association (NYHA) class increased as follows: 90.2 +/- 15.4% in class I, 76.9 
      +/- 13.8% in class II, and 59.7 +/- 11.9% in class III (mean +/- SD). Although 
      the ratio of increase in oxygen uptake to work-rate increment was not influenced 
      by age or sex, it decreased as the severity of heart disease progressed. These 
      results suggest that indexes from cardiopulmonary exercise testing are closely 
      related to the pathophysiology of heart failure. We conclude that these indexes 
      can be used as objective and reliable parameters for evaluation of the severity 
      of heart failure in terms of functional capacity.
FAU - Itoh, H
AU  - Itoh H
AD  - Second Department of Internal Medicine, Tokyo Medical and Dental University, 
      Japan.
FAU - Taniguchi, K
AU  - Taniguchi K
FAU - Koike, A
AU  - Koike A
FAU - Doi, M
AU  - Doi M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
MH  - Anaerobic Threshold/*physiology
MH  - Electrocardiography
MH  - Exercise Test/methods
MH  - Female
MH  - Heart Failure/*diagnosis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Gas Exchange/*physiology
MH  - Spirometry
MH  - Ventilation-Perfusion Ratio
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
PST - ppublish
SO  - Circulation. 1990 Jan;81(1 Suppl):II31-7.