PMID- 22951602 OWN - NLM STAT- MEDLINE DCOM- 20130311 LR - 20161125 IS - 2040-3372 (Electronic) IS - 2040-3364 (Linking) VI - 4 IP - 20 DP - 2012 Oct 21 TI - An excellent enzymatic lactic acid biosensor with ZnO nanowires-gated AlGaAs/GaAs high electron mobility transistor. PG - 6415-8 AB - An excellent biosensor with ZnO nanowires-gated AlGaAs/GaAs high electron mobility transistor (HEMT) was used to detect lactic acid. Due to the new structure, addition of the Si-doped GaAs cap layer, the HEMT biosensor could detect a wide range of lactic acid concentrations from 0.03 nM to 300 mM. The novel biosensor exhibiting good performance along with fast response, high sensitivity, wide detection range, and long-term stability, can be integrated with a commercially available transmitter to realize lactic acid detection. FAU - Ma, Siwei AU - Ma S AD - State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, People's Republic of China. FAU - Liao, Qingliang AU - Liao Q FAU - Liu, Hanshuo AU - Liu H FAU - Song, Yu AU - Song Y FAU - Li, Ping AU - Li P FAU - Huang, Yunhua AU - Huang Y FAU - Zhang, Yue AU - Zhang Y LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Nanoscale JT - Nanoscale JID - 101525249 RN - 0 (Arsenicals) RN - 0 (Enzymes, Immobilized) RN - 27FC46GA44 (gallium arsenide) RN - 33X04XA5AT (Lactic Acid) RN - CH46OC8YV4 (Gallium) RN - CPD4NFA903 (Aluminum) RN - EC 1.- (Mixed Function Oxygenases) RN - EC 1.13.12.4 (lactate 2-monooxygenase) RN - SOI2LOH54Z (Zinc Oxide) SB - IM MH - Aluminum/*chemistry MH - Arsenicals/*chemistry MH - Biosensing Techniques/*instrumentation/methods MH - Enzymes, Immobilized/*chemistry/metabolism MH - Gallium/*chemistry MH - Lactic Acid/*analysis/metabolism MH - Limit of Detection MH - Mixed Function Oxygenases/chemistry/metabolism MH - Nanowires/*chemistry MH - Zinc Oxide/*chemistry EDAT- 2012/09/07 06:00 MHDA- 2013/03/12 06:00 CRDT- 2012/09/07 06:00 PHST- 2012/09/07 06:00 [entrez] PHST- 2012/09/07 06:00 [pubmed] PHST- 2013/03/12 06:00 [medline] AID - 10.1039/c2nr31708g [doi] PST - ppublish SO - Nanoscale. 2012 Oct 21;4(20):6415-8. doi: 10.1039/c2nr31708g.