PMID- 2295675 OWN - NLM STAT- MEDLINE DCOM- 19900221 LR - 20160512 IS - 0021-9355 (Print) IS - 0021-9355 (Linking) VI - 72 IP - 1 DP - 1990 Jan TI - HLA phenotypes in patients who have osteosarcoma. PG - 68-70 AB - Human leukocyte antigen (HLA) phenotypes were studied in twenty Japanese patients who had typical osteosarcoma. The HLA-A11 phenotype was found in ten (50 per cent) of the twenty patients, compared with 16.6 per cent of 235 control subjects (chi square = 13.248; p less than 0.0005)--an odds ratio of 5.026. These data suggest that major histocompatibility complex-linked genes may determine susceptibility to osteosarcoma. FAU - Shimizu, T AU - Shimizu T AD - Department of Orthopaedic Surgery, Gunma University School of Medicine, Japan. FAU - Chigira, M AU - Chigira M FAU - Nagase, M AU - Nagase M FAU - Watanabe, H AU - Watanabe H FAU - Udagawa, E AU - Udagawa E LA - eng PT - Journal Article PL - United States TA - J Bone Joint Surg Am JT - The Journal of bone and joint surgery. American volume JID - 0014030 RN - 0 (HLA Antigens) RN - 0 (HLA-A Antigens) RN - 0 (HLA-A11 Antigen) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Bone Neoplasms/genetics/*immunology MH - Child MH - Female MH - HLA Antigens/*analysis/genetics MH - HLA-A Antigens/analysis/genetics MH - HLA-A11 Antigen MH - Humans MH - Male MH - Middle Aged MH - Osteosarcoma/genetics/*immunology MH - Phenotype MH - Prognosis EDAT- 1990/01/01 00:00 MHDA- 1990/01/01 00:01 CRDT- 1990/01/01 00:00 PHST- 1990/01/01 00:00 [pubmed] PHST- 1990/01/01 00:01 [medline] PHST- 1990/01/01 00:00 [entrez] PST - ppublish SO - J Bone Joint Surg Am. 1990 Jan;72(1):68-70.