PMID- 22960950
OWN - NLM
STAT- MEDLINE
DCOM- 20130123
LR  - 20221207
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Print)
IS  - 0960-8923 (Linking)
VI  - 22
IP  - 10
DP  - 2012 Oct
TI  - Clinical efficacy of laparoscopic sleeve gastrectomy vs laparoscopic gastric 
      bypass in obese type 2 diabetic patients: a retrospective comparison.
PG  - 1535-9
LID - 10.1007/s11695-012-0657-5 [doi]
AB  - BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are 
      performed in patients with obesity and type 2 diabetes mellitus (T2DM). The aim 
      of this study is to evaluate retrospectively the clinical efficacy of RYGB and SG 
      in two groups of obese T2DM patients. METHODS: From the hospital database, we 
      extracted the clinical records of 31 obese T2DM patients, of whom 15 (7 F/8 M) 
      had undergone laparoscopic SG (LSG) and 16 (7 F/9 M) laparoscopic RYGB (LRYGB) in 
      the period 2005-2008. The groups were comparable for age (range 33-59 years) and 
      BMI (range 38-57 kg/m(2)). LRYGB alimentary limb was 150 cm, and biliopancreatic 
      limb was 150 cm from the Treitz ligament. LSG vertical transection was calibrated 
      on a 40-Fr orogastric bougie. Data were analysed at 6, 12 and 18-24 months with 
      reference to weight loss and remission of comorbidities. RESULTS: The reduction 
      in body weight was comparable in the two groups. At 18-24 months the percent BMI 
      reduction was 29 +/- 8 and 33 +/- 11 % in LSG and LRYGB, respectively. Percent excess 
      weight loss was 53 +/- 16 and 52 +/- 19 % in LSG and LRYGB, respectively. Thirteen 
      patients in LSG and 14 patients in LRYGB discontinued their hypoglycaemic 
      medications. Five (55 %) patients in LSG and eight (89 %) in LRYGB discontinued 
      antihypertensive drugs. Three out of five patients in LSG and one out of two 
      patients in LRYGB withdrew lipid-lowering agents. CONCLUSIONS: LSG and LRYGB are 
      equally effective in terms of weight loss and remission of obesity-related 
      comorbidities. Controlled long-term comparisons are needed to establish the 
      optimal procedure in relation to patients' characteristics.
FAU - Cutolo, P P
AU  - Cutolo PP
AD  - General and Laparoscopic Surgery Unit, S. Giovanni Bosco Hospital, Naples, Italy. 
      pierpaolo@cutolo.it
FAU - Nosso, G
AU  - Nosso G
FAU - Vitolo, G
AU  - Vitolo G
FAU - Brancato, V
AU  - Brancato V
FAU - Capaldo, B
AU  - Capaldo B
FAU - Angrisani, L
AU  - Angrisani L
LA  - eng
GR  - KL2 RR025757/RR/NCRR NIH HHS/United States
GR  - 1KL2RR025757-01/RR/NCRR NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Comorbidity
MH  - Diabetes Mellitus, Type 2/metabolism/physiopathology
MH  - Dyslipidemias/metabolism/physiopathology
MH  - Female
MH  - *Gastric Bypass/methods
MH  - *Gastroplasty/methods
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Hypertension/metabolism/physiopathology
MH  - Italy/epidemiology
MH  - *Laparoscopy
MH  - Male
MH  - Middle Aged
MH  - Obesity, Morbid/metabolism/physiopathology/*surgery
MH  - Patient Selection
MH  - Remission Induction
MH  - Retrospective Studies
MH  - Sleep Apnea Syndromes
MH  - Treatment Outcome
MH  - Weight Loss
PMC - PMC4197913
MID - NIHMS510936
EDAT- 2012/09/11 06:00
MHDA- 2013/01/24 06:00
PMCR- 2014/10/15
CRDT- 2012/09/11 06:00
PHST- 2012/09/11 06:00 [entrez]
PHST- 2012/09/11 06:00 [pubmed]
PHST- 2013/01/24 06:00 [medline]
PHST- 2014/10/15 00:00 [pmc-release]
AID - 10.1007/s11695-012-0657-5 [doi]
PST - ppublish
SO  - Obes Surg. 2012 Oct;22(10):1535-9. doi: 10.1007/s11695-012-0657-5.