PMID- 22966435
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20120912
LR  - 20220318
IS  - 2090-2093 (Electronic)
IS  - 2090-2085 (Print)
IS  - 2090-2093 (Linking)
VI  - 2012
DP  - 2012
TI  - Treatment adherence with early prescription of long-acting injectable 
      antipsychotics in recent-onset schizophrenia.
PG  - 368687
LID - 10.1155/2012/368687 [doi]
LID - 368687
AB  - Although response to treatment for the first episode of schizophrenia is 
      generally favourable, nonadherence with the treatment is the first cause of 
      relapse and rehospitalisation within the next few years. Long-acting injectable 
      antipsychotics (LAIAs) combine the advantages of the newer antipsychotics and the 
      long-acting formulation. The evaluation concerns 25 schizophrenic patients 
      hospitalised for the first time, treated with risperidone long-acting injectable 
      (RLAI) associated with reintegration methods, and followed up for at least 18 
      months. Clinical observation was completed using Clinical Global Impression (CGI) 
      scale and Global Assessment of Functioning (GAF). Clinical improvement was 
      coupled with a good reintegration rate, very few relapse, or rehospitalisation. 
      Bimonthly injection combined with psychosocial methods improved interactive 
      followup, and therefore patients' compliance with the treatment. Treating with 
      LAIA as early as possible, from the first episode if possible, can reduce 
      relapse, number and duration of rehospitalisation, and cognitive symptoms and 
      improve the quality of life and prognosis.
FAU - Viala, Annie
AU  - Viala A
AD  - SM 13, Centre Hospitalier Sainte-Anne, 1 Rue Cabanis, 75014 Paris, France.
FAU - Cornic, Francoise
AU  - Cornic F
FAU - Vacheron, Marie-Noelle
AU  - Vacheron MN
LA  - eng
PT  - Journal Article
DEP - 20120403
PL  - Egypt
TA  - Schizophr Res Treatment
JT  - Schizophrenia research and treatment
JID - 101576450
PMC - PMC3420640
EDAT- 2012/09/12 06:00
MHDA- 2012/09/12 06:01
PMCR- 2012/04/03
CRDT- 2012/09/12 06:00
PHST- 2011/12/05 00:00 [received]
PHST- 2012/01/20 00:00 [revised]
PHST- 2012/01/29 00:00 [accepted]
PHST- 2012/09/12 06:00 [entrez]
PHST- 2012/09/12 06:00 [pubmed]
PHST- 2012/09/12 06:01 [medline]
PHST- 2012/04/03 00:00 [pmc-release]
AID - 10.1155/2012/368687 [doi]
PST - ppublish
SO  - Schizophr Res Treatment. 2012;2012:368687. doi: 10.1155/2012/368687. Epub 2012 
      Apr 3.