PMID- 2296854
OWN - NLM
STAT- MEDLINE
DCOM- 19900214
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 119
IP  - 1
DP  - 1990 Jan
TI  - Serial evaluation of ventricular function after percutaneous aortic balloon 
      valvuloplasty.
PG  - 130-5
AB  - To evaluate the serial changes in right and left ventricular performance after 
      percutaneous aortic balloon valvuloplasty, 15 patients, mean age 75 +/- 18 years, 
      and in New York Heart Association (NYHA) class III, were studied with first-pass 
      radionuclide angiocardiography (RNA) immediately before, then 5 minutes, 2 hours, 
      4 hours, 6 hours, and 3 days after valvuloplasty. No change was observed in heart 
      rate, aortic root systolic pressure, Fick, or RNA cardiac output, amount of 
      aortic insufficiency measured either angiographically or with the regurgitant 
      fraction determination immediately after valvuloplasty. However, significant 
      changes were observed in the peak-to-peak aortic valve gradient (63 to 35 mm Hg; 
      p less than 0.001), mean aortic valve gradient (54 to 33 mm Hg; p less than 
      0.001), aortic valve area (0.60 to 0.90 cm2; p less than 0.001), and meridional 
      wall stress (79 to 50 10(3) dynes/cm2; p less than 0.01) immediately following 
      valvuloplasty. In addition, left ventricular end-diastolic volume decreased from 
      186 to 153 ml (p less than 0.001), end-systolic volume decreased from 114 to 86 
      ml (p less than 0.001), micromanometric left ventricular end-diastolic pressure 
      decreased from 20 to 14 mm Hg (p less than 0.02), and left ventricular ejection 
      fraction increased from 0.39 to 0.45 (p less than 0.001). Peak positive left 
      ventricular dP/dt and end-systolic pressure-volume ratio did not change after 
      valvuloplasty (1700 to 1550 mm Hg/sec, 2.1 to 2.5 mm Hg/ml, 
      respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Harpole, D H
AU  - Harpole DH
AD  - Department of Surgery, Duke University Medical Center, Durham, NC 27710.
FAU - Davidson, C
AU  - Davidson C
FAU - Skelton, T
AU  - Skelton T
FAU - Jones, R H
AU  - Jones RH
FAU - Bashore, T M
AU  - Bashore TM
LA  - eng
GR  - HL17670/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Angiocardiography
MH  - Aortic Valve Stenosis/diagnostic imaging/physiopathology/*therapy
MH  - *Catheterization
MH  - Female
MH  - *Heart Function Tests
MH  - Heart Ventricles
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Radionuclide Imaging
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
AID - S0002-8703(05)80092-4 [pii]
AID - 10.1016/s0002-8703(05)80092-4 [doi]
PST - ppublish
SO  - Am Heart J. 1990 Jan;119(1):130-5. doi: 10.1016/s0002-8703(05)80092-4.