PMID- 22969281
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Print)
IS  - 1177-5467 (Linking)
VI  - 6
DP  - 2012
TI  - Choroidal excavation with polypoidal choroidal vasculopathy: a case report.
PG  - 1373-6
LID - 10.2147/OPTH.S33879 [doi]
AB  - PURPOSE: This is a report of a case of choroidal excavation accompanied by 
      polypoidal choroidal vasculopathy (PCV) and retinal pigment epithelium detachment 
      (PED). METHODS: A 57-year-old Japanese woman who had begun complaining of 
      metamorphopsia in her left eye 7 months earlier underwent spectral-domain optical 
      coherence tomography (SD-OCT), fluorescein angiography (FA), and indocyanine 
      green angiography (IA), as well as a routine ophthalmological examination. 
      RESULTS: The patient's intraocular pressure, visual acuity, and visual field were 
      within normal range. Ophthalmoscopy revealed a serous macular detachment, soft 
      drusen, exudates, and a reddish-orange elevated lesion in the macula of the left 
      eye. The right eye was normal. SD-OCT revealed two lesions in the left eye. One 
      was a PED accompanied by a notch sign, and the other was a choroidal excavation. 
      Additionally, FA revealed a window defect in the PED, and IA showed typical PCV. 
      Three monthly injections of antivascular endothelial growth factor preserved 
      visual acuity, but failed to have any visible effect on the lesion during the 
      6-month follow up period. CONCLUSIONS: This is the first report of choroidal 
      excavation accompanied by PED and PCV. The data suggest that choroidal excavation 
      may be associated with various changes that have not been previously reported. 
      Careful observation of such cases may therefore be necessary.
FAU - Kobayashi, Wataru
AU  - Kobayashi W
AD  - Department of Ophthalmology, Tohoku University Graduate School of Medical 
      Science, Sendai, Japan.
FAU - Abe, Toshiaki
AU  - Abe T
FAU - Tamai, Hiroshi
AU  - Tamai H
FAU - Nakazawa, Toru
AU  - Nakazawa T
LA  - eng
PT  - Case Reports
DEP - 20120827
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC3437952
OTO - NOTNLM
OT  - anti-vascular endothelial growth factor treatment
OT  - choroidal excavation
OT  - polypoidal choroidal vasculopathy
EDAT- 2012/09/13 06:00
MHDA- 2012/09/13 06:01
PMCR- 2012/08/27
CRDT- 2012/09/13 06:00
PHST- 2012/09/13 06:00 [entrez]
PHST- 2012/09/13 06:00 [pubmed]
PHST- 2012/09/13 06:01 [medline]
PHST- 2012/08/27 00:00 [pmc-release]
AID - opth-6-1373 [pii]
AID - 10.2147/OPTH.S33879 [doi]
PST - ppublish
SO  - Clin Ophthalmol. 2012;6:1373-6. doi: 10.2147/OPTH.S33879. Epub 2012 Aug 27.