PMID- 22973304
OWN - NLM
STAT- MEDLINE
DCOM- 20130130
LR  - 20211021
IS  - 1687-5303 (Electronic)
IS  - 1687-5214 (Print)
IS  - 1687-5214 (Linking)
VI  - 2012
DP  - 2012
TI  - Vascular disease in diabetic women: Why do they miss the female protection?
PG  - 570598
LID - 10.1155/2012/570598 [doi]
LID - 570598
AB  - Gender plays a pivotal role in the onset as well as in the progression of the 
      cardiovascular disease with a higher morbidity and mortality being detected in 
      men with respect to women. Type 2 Diabetes Mellitus (T2DM) may reduce 
      gender-related differences in the prevalence of cardiovascular disease by fading 
      the vascular protective effects afforded by estrogen in females. This article 
      will discuss the role of sex and sex hormones on the incidence and mechanisms 
      involved in vascular dysfunction associated to T2DM, which might explain why 
      women with T2DM lack the vascular protection.
FAU - Dantas, Ana Paula Villela
AU  - Dantas AP
AD  - Experimental Cardiology Division, Institut d'Investigacions Biomediques August Pi 
      i Sunyer (IDIBAPS) and Institut Clinic de Torax, C/Casanova 143 Laboratory, 
      IDIBAPS 404, Hospital Clinic, 08036 Barcelona, Spain. adantas@clinic.ub.es
FAU - Fortes, Zuleica Bruno
AU  - Fortes ZB
FAU - de Carvalho, Maria Helena Catelli
AU  - de Carvalho MH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20120903
PL  - United States
TA  - Exp Diabetes Res
JT  - Experimental diabetes research
JID - 101274844
SB  - IM
MH  - Aged
MH  - Animals
MH  - Cardiovascular Diseases/complications/epidemiology/etiology/prevention & control
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Diabetic Angiopathies/*epidemiology/etiology/prevention & control
MH  - Female
MH  - Humans
MH  - Male
MH  - Risk Factors
MH  - Sex Factors
MH  - Vascular Diseases/*complications/epidemiology/etiology/prevention & control
MH  - *Women's Health
PMC - PMC3438753
EDAT- 2012/09/14 06:00
MHDA- 2013/01/31 06:00
PMCR- 2012/09/03
CRDT- 2012/09/14 06:00
PHST- 2012/06/02 00:00 [received]
PHST- 2012/08/02 00:00 [accepted]
PHST- 2012/09/14 06:00 [entrez]
PHST- 2012/09/14 06:00 [pubmed]
PHST- 2013/01/31 06:00 [medline]
PHST- 2012/09/03 00:00 [pmc-release]
AID - 10.1155/2012/570598 [doi]
PST - ppublish
SO  - Exp Diabetes Res. 2012;2012:570598. doi: 10.1155/2012/570598. Epub 2012 Sep 3.