PMID- 22982224
OWN - NLM
STAT- MEDLINE
DCOM- 20130426
LR  - 20221207
IS  - 1873-6750 (Electronic)
IS  - 0160-4120 (Linking)
VI  - 49
DP  - 2012 Nov 15
TI  - A methodology for evaluating the influence of diets and intergenerational dietary 
      transitions on historic and future human exposure to persistent organic 
      pollutants in the Arctic.
PG  - 83-91
LID - S0160-4120(12)00188-2 [pii]
LID - 10.1016/j.envint.2012.08.014 [doi]
AB  - Concentrations of persistent organic pollutants (POPs) in Inuit populations have 
      been observed to decrease over the last decade. The main objective of this study 
      was to develop a methodology to quantify the potential influence of 
      intergenerational dietary transitions on human exposure to organic contaminants 
      in the Arctic environment using PCB-153 as a case study. Long-term (1930-2050) 
      dynamic simulations using realistic emission estimates were conducted using 
      linked chemical fate and bioaccumulation models. Female body burdens were 
      calculated over time assuming five diets with varying proportions of traditional 
      and imported food items and then used to illustrate the potential variability at 
      a community/population level. At any given time point, individuals consuming a 
      100% traditional diet (i.e. high intake of ringed seal blubber) have modelled 
      body burdens approximately 15-150 times higher than individuals consuming a 100% 
      imported food diet. Consumption of locally-harvested fish (e.g. Arctic cod) and 
      seal meat are also associated with comparatively low body burdens. Decreased 
      emissions are predicted to decrease the PCB-153 body burden of 30-year old 
      females by 6 to 13-fold from 1980 to 2020 with dietary transitions accounting for 
      an additional factor of 2-50 (i.e. 12-650 times lower in total) depending on the 
      type of dietary transition and the origin of the imported food items. The model 
      results indicate that dietary transitions are an important factor underlying the 
      variability within and between subpopulations in addition to partially explaining 
      the observed temporal trends. Specific information on the nature and timing of 
      dietary transitions is highly valuable when interpreting biomonitoring data.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Quinn, Cristina L
AU  - Quinn CL
AD  - Department of Physical and Environmental Sciences, University of Toronto 
      Scarborough, Toronto, Ontario M1C 1A4, Canada.
FAU - Armitage, James M
AU  - Armitage JM
FAU - Breivik, Knut
AU  - Breivik K
FAU - Wania, Frank
AU  - Wania F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120914
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
RN  - 0 (Environmental Pollutants)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - ZRU0C9E32O (2,4,5,2',4',5'-hexachlorobiphenyl)
SB  - IM
MH  - Adult
MH  - Animals
MH  - Arctic Regions
MH  - Body Burden
MH  - Diet/*statistics & numerical data
MH  - Environmental Exposure/*statistics & numerical data
MH  - Environmental Pollutants/*analysis
MH  - Environmental Pollution/statistics & numerical data
MH  - Female
MH  - Food Contamination/statistics & numerical data
MH  - Forecasting
MH  - Humans
MH  - Inuit
MH  - Meat/analysis/statistics & numerical data
MH  - Polychlorinated Biphenyls/analysis
MH  - Young Adult
EDAT- 2012/09/18 06:00
MHDA- 2013/04/27 06:00
CRDT- 2012/09/18 06:00
PHST- 2012/07/12 00:00 [received]
PHST- 2012/08/20 00:00 [revised]
PHST- 2012/08/21 00:00 [accepted]
PHST- 2012/09/18 06:00 [entrez]
PHST- 2012/09/18 06:00 [pubmed]
PHST- 2013/04/27 06:00 [medline]
AID - S0160-4120(12)00188-2 [pii]
AID - 10.1016/j.envint.2012.08.014 [doi]
PST - ppublish
SO  - Environ Int. 2012 Nov 15;49:83-91. doi: 10.1016/j.envint.2012.08.014. Epub 2012 
      Sep 14.