PMID- 22983884
OWN - NLM
STAT- MEDLINE
DCOM- 20130731
LR  - 20220331
IS  - 1868-4297 (Electronic)
IS  - 1868-4297 (Linking)
VI  - 28
IP  - 1
DP  - 2013 Jan
TI  - Current treatment of ST elevation acute myocardial infarction in Japan: 
      door-to-balloon time and total ischemic time from the J-AMI registry.
PG  - 30-6
LID - 10.1007/s12928-012-0128-x [doi]
AB  - The door-to-balloon time and total ischemic time are important predictors of the 
      outcome in patients with ST elevation myocardial infarction (STEMI) receiving 
      primary angioplasty, but the current situation in Japan is unknown. The Japan 
      Acute Myocardial Infarction registry is a prospective observational study of 
      2,030 consecutive STEMI patients admitted to 213 Japanese institutions. The time 
      from symptom onset to hospital arrival, door-to-balloon time, and in-hospital 
      outcome were assessed. Data were compared between patients treated during regular 
      hours or after hours. Percutaneous coronary angioplasty was done in 97.2 % of the 
      patients, using drug-eluting stents in 30 % and bare metal stents in 63 % of the 
      treated cases. The median symptom onset-to-door time (25th and 75th percentiles) 
      was 135 min (64-305 min), median door-to-balloon time was 42 min (28-66 min), and 
      mean procedural time was 98 +/- 51 min. The on-call catheterization team performed 
      48.5 % of the procedures. There was no significant difference of door-to-balloon 
      time between the patients treated after hours and those treated during regular 
      hours. The cardiac mortality rate was 3.2 %, and it increased with longer 
      door-to-balloon times (P = 0.03). The relationship between total ischemic time 
      and cardiac mortality showed 2 peaks, with a trough at 5 h. Median 
      door-to-balloon time was <90 min and was not longer in after hours cases. These 
      findings suggest that Japanese institutions can provide primary angioplasty 
      within an acceptable time frame.
FAU - Nakamura, Masato
AU  - Nakamura M
AD  - Department of Cardiovascular Medicine, Ohashi Medical Center, Toho University, 
      Tokyo, Japan. masato@oha.toho-u.ac.jp
FAU - Yamagishi, Masakazu
AU  - Yamagishi M
FAU - Ueno, Takafumi
AU  - Ueno T
FAU - Hara, Kazuhiro
AU  - Hara K
FAU - Ishiwata, Sugao
AU  - Ishiwata S
FAU - Itoh, Tomonori
AU  - Itoh T
FAU - Hamanaka, Ichiro
AU  - Hamanaka I
FAU - Wakatsuki, Tetsuzo
AU  - Wakatsuki T
FAU - Sugano, Teruyasu
AU  - Sugano T
FAU - Kawai, Kazuya
AU  - Kawai K
FAU - Kimura, Takeshi
AU  - Kimura T
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20120916
PL  - Japan
TA  - Cardiovasc Interv Ther
JT  - Cardiovascular intervention and therapeutics
JID - 101522043
SB  - IM
EIN - Cardiovasc Interv Ther. 2013 Oct;28(4):427. Wakatsuki, Tetuszo [corrected to 
      Wakatsuki, Tetsuzo]
MH  - Aged
MH  - Aged, 80 and over
MH  - Angioplasty, Balloon, Coronary/*methods
MH  - Female
MH  - Hospital Mortality
MH  - Hospitalization
MH  - Humans
MH  - Japan
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/mortality/*therapy
MH  - Prospective Studies
MH  - Registries
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2012/09/18 06:00
MHDA- 2013/08/01 06:00
CRDT- 2012/09/18 06:00
PHST- 2012/03/07 00:00 [received]
PHST- 2012/08/07 00:00 [accepted]
PHST- 2012/09/18 06:00 [entrez]
PHST- 2012/09/18 06:00 [pubmed]
PHST- 2013/08/01 06:00 [medline]
AID - 10.1007/s12928-012-0128-x [doi]
PST - ppublish
SO  - Cardiovasc Interv Ther. 2013 Jan;28(1):30-6. doi: 10.1007/s12928-012-0128-x. Epub 
      2012 Sep 16.