PMID- 22985128
OWN - NLM
STAT- MEDLINE
DCOM- 20130729
LR  - 20220210
IS  - 1525-1403 (Electronic)
IS  - 1094-7159 (Linking)
VI  - 16
IP  - 1
DP  - 2013 Jan-Feb
TI  - Efficacy and effectiveness of percutaneous tibial nerve stimulation in the 
      treatment of pelvic organ disorders: a systematic review.
PG  - 25-33; discussion 33
LID - 10.1111/j.1525-1403.2012.00504.x [doi]
AB  - OBJECTIVE: This systematic review aimed to determine the efficacy and 
      effectiveness of percutaneous tibial nerve stimulation (PTNS) on symptoms of 
      overactive bladder (OAB) and pelvic organ disorders, pain, adverse events (AEs), 
      and quality of life (QoL). METHODS: A literature search was performed in 
      September 2011 in the databases MEDLINE, CINAHL, and EMBASE. Hand searching of 
      references was conducted. Only randomized controlled trials (RCTs) and controlled 
      clinical trials (CCTs) with adult patients were included. RESULTS: Seven studies 
      met the eligibility criteria. Five RCTs indicated improvement (range 36.7-80%) on 
      OAB symptoms, frequency, urgency, nocturia, and incontinence. One CCT reported 
      improvement (mean 15.7) in 53% of the subjects on fecal incontinence (FI) 
      symptoms on an FI Questionnaire (range 0-20). One RCT showed more than 50% 
      improvement on pain (40%) and symptom scores (66.6%) in chronic pelvic pain 
      (CPP). Limitations are the small amount, overall low quality, and variety in 
      outcome measures of included studies. Only minor AEs were reported. No 
      meta-analysis was performed as a consequence of heterogeneous data. CONCLUSIONS: 
      This systematic review provides evidence for the efficacy of PTNS on symptoms, 
      pain, and QoL measures of OAB, FI and category IIIB CP/CPP. Evidence of 
      effectiveness was found on symptoms and QoL for OAB. The total amount of seven 
      included studies, from which even the most favorable study has some potential 
      bias, is too small to draw firm conclusions. Independent high quality RCTs are 
      necessary to confirm and delineate the range of therapeutic effects of PTNS in 
      this region. PTNS is a safe intervention.
CI  - (c) 2012 International Neuromodulation Society.
FAU - Biemans, Johanna M A E
AU  - Biemans JM
AD  - Department of Urology, Netherlands Rijnstate Hospital, Arnhem, the Netherlands. 
      info@ptnsbijoveractieveblaas.nl
FAU - van Balken, Michael R
AU  - van Balken MR
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20120917
PL  - United States
TA  - Neuromodulation
JT  - Neuromodulation : journal of the International Neuromodulation Society
JID - 9804159
SB  - IM
MH  - Clinical Trials as Topic
MH  - Fecal Incontinence/*therapy
MH  - Humans
MH  - Pelvic Pain/*therapy
MH  - Quality of Life
MH  - Tibial Nerve
MH  - *Transcutaneous Electric Nerve Stimulation
MH  - Urinary Bladder, Overactive/*therapy
EDAT- 2012/09/19 06:00
MHDA- 2013/07/31 06:00
CRDT- 2012/09/19 06:00
PHST- 2012/09/19 06:00 [entrez]
PHST- 2012/09/19 06:00 [pubmed]
PHST- 2013/07/31 06:00 [medline]
AID - S1094-7159(13)60005-7 [pii]
AID - 10.1111/j.1525-1403.2012.00504.x [doi]
PST - ppublish
SO  - Neuromodulation. 2013 Jan-Feb;16(1):25-33; discussion 33. doi: 
      10.1111/j.1525-1403.2012.00504.x. Epub 2012 Sep 17.