PMID- 22988381
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 1998-3565 (Electronic)
IS  - 0973-6247 (Print)
IS  - 0973-6247 (Linking)
VI  - 6
IP  - 2
DP  - 2012 Jul
TI  - Analysis of adverse events and predisposing factors in voluntary and replacement 
      whole blood donors: A study from north India.
PG  - 155-60
LID - 10.4103/0973-6247.98922 [doi]
AB  - BACKGROUND: Lack of awareness and community motivation, compounded with 
      fragmented blood transfusion services in our country, Often leads to shortage of 
      blood. Donor recruitment and retention are essential for ensuring adequate blood 
      supply. However, adverse events (AEs) in donors have a negative impact on donor 
      return. AIMS AND OBJECTIVES: The present study was aimed to assess the frequency 
      of AEs in whole blood donors and analyze the predisposing factors for AEs. 
      MATERIAL AND METHODS: The study was conducted on allogeneic whole blood donors 
      over a period of 14 months, i.e., from January 2002 to February 2003. A total of 
      37,896 donors were monitored for any AEs: 22587 (59.6%) were voluntary donors 
      (VD) and 15,309 (40.4%) were replacement donors (RD). RESULTS: Overall reaction 
      rate was 2.5% with vasovagal reactions constituting 63.5% and hematomas 35.0% of 
      all reactions. Vasovagal reactions showed a significant association with young 
      age, lower weight, first time donation status, female gender, and nature of blood 
      donation camps. Amongst male donors, RDs had more reactions (P=0.03) than VDs. 
      Majority of donors (85%) with vasovagal reactions admitted to some fear or 
      anxiety prior to donation. Hematoma formation occurred significantly more when 
      less trained staff performed phlebotomy. CONCLUSION: Donor safety is an essential 
      prerequisite to increase voluntary blood donation. AE analysis helps in 
      identifying the blood donors at risk of donor reactions and adopting appropriate 
      donor motivational strategies, pre-donation counseling, and care during and after 
      donation.
FAU - Agnihotri, Naveen
AU  - Agnihotri N
AD  - Department of Transfusion Medicine, PGIMER, Chandigarh, India ; Blood Bank and 
      Transfusion Services, Fortis Hospital, Delhi, India.
FAU - Marwaha, Neelam
AU  - Marwaha N
FAU - Sharma, Ratti R
AU  - Sharma RR
LA  - eng
PT  - Journal Article
PL  - India
TA  - Asian J Transfus Sci
JT  - Asian journal of transfusion science
JID - 101306858
PMC - PMC3439755
OTO - NOTNLM
OT  - Adverse events
OT  - donors
OT  - vasovagal reactions
COIS- Conflict of Interest: None declared.
EDAT- 2012/09/19 06:00
MHDA- 2012/09/19 06:01
PMCR- 2012/07/01
CRDT- 2012/09/19 06:00
PHST- 2012/09/19 06:00 [entrez]
PHST- 2012/09/19 06:00 [pubmed]
PHST- 2012/09/19 06:01 [medline]
PHST- 2012/07/01 00:00 [pmc-release]
AID - AJTS-6-155 [pii]
AID - 10.4103/0973-6247.98922 [doi]
PST - ppublish
SO  - Asian J Transfus Sci. 2012 Jul;6(2):155-60. doi: 10.4103/0973-6247.98922.