PMID- 22995752 OWN - NLM STAT- MEDLINE DCOM- 20121231 LR - 20220331 IS - 1532-2165 (Electronic) IS - 1078-5884 (Linking) VI - 44 IP - 5 DP - 2012 Nov TI - Limited economic evidence of carotid artery stenosis diagnosis and treatment: a systematic review. PG - 505-13 LID - S1078-5884(12)00597-7 [pii] LID - 10.1016/j.ejvs.2012.08.010 [doi] AB - The objective of this article is to assess the availability and validity of economic evaluations of carotid artery stenosis (CS) diagnosis and treatment. DESIGN: Systematic review of economic evaluations of the diagnosis and treatment of CS. METHODS: Systematic review of full economic evaluations published in Medline and Google Scholar up until 28 February 2012. Based on economic checklists (Evers and Philips), the identified studies were classified as high, medium, or low quality. RESULTS: Twenty-three evaluations were identified. The study quality ranged from 26% to 84% of all achievable points (Evers). Seven studies were of high, eight of medium and eight of low quality. No comparison was made between carotid angioplasty and stenting (CAS) and best medical treatment (BMT). For subjects with severe stenosis, comparisons of carotid endarterectomy (CEA) and BMT were also missing. Three of five studies dealing with pre-operative imaging found that duplex Doppler ultrasound (US) was cost-effective compared with carotid angiogram (AG). CONCLUSIONS: There is a huge lack of high-quality studies and of studies that confirm published results. Also, for a given study quality, the most cost-effective treatment strategy is still unknown in some cases ('CAS' vs. 'BMT', 'US combined with magnetic resonance angiography supplemented with AG' vs. 'US combined with computer tomography angiography'). CI - Copyright (c) 2012 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved. FAU - Shenoy, A U AU - Shenoy AU AD - Helmholtz Zentrum Munchen, Institute of Health Economics and Health Care Management, Neuherberg, Germany. FAU - Aljutaili, M AU - Aljutaili M FAU - Stollenwerk, B AU - Stollenwerk B LA - eng PT - Journal Article PT - Review PT - Systematic Review DEP - 20120918 PL - England TA - Eur J Vasc Endovasc Surg JT - European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery JID - 9512728 SB - IM MH - Angioplasty, Balloon/adverse effects/*economics MH - Carotid Stenosis/diagnosis/*economics/therapy MH - Checklist MH - Cost-Benefit Analysis MH - Diagnostic Techniques, Cardiovascular/*economics MH - Endarterectomy, Carotid/adverse effects/*economics MH - Humans MH - Magnetic Resonance Angiography/economics MH - Models, Economic MH - Outcome and Process Assessment, Health Care/*economics MH - Predictive Value of Tests MH - Severity of Illness Index MH - Tomography, X-Ray Computed/economics MH - Treatment Outcome MH - Ultrasonography, Doppler, Duplex/economics EDAT- 2012/09/22 06:00 MHDA- 2013/01/01 06:00 CRDT- 2012/09/22 06:00 PHST- 2012/02/03 00:00 [received] PHST- 2012/08/26 00:00 [accepted] PHST- 2012/09/22 06:00 [entrez] PHST- 2012/09/22 06:00 [pubmed] PHST- 2013/01/01 06:00 [medline] AID - S1078-5884(12)00597-7 [pii] AID - 10.1016/j.ejvs.2012.08.010 [doi] PST - ppublish SO - Eur J Vasc Endovasc Surg. 2012 Nov;44(5):505-13. doi: 10.1016/j.ejvs.2012.08.010. Epub 2012 Sep 18.