PMID- 22997554
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20120924
LR  - 20240316
IS  - 2074-1812 (Electronic)
IS  - 2074-1804 (Print)
IS  - 2074-1804 (Linking)
VI  - 14
IP  - 7
DP  - 2012 Jul
TI  - Accuracy of Various Iron Parameters in the Prediction of Iron Deficiency Anemia 
      among Healthy Women of Child Bearing Age, Saudi Arabia.
PG  - 397-401
AB  - BACKGROUND: Iron deficiency is still considered the most common nutritional 
      deficiency worldwide and the most significant negative consequence of iron 
      deficiency is iron deficiency anemia (IDA). This study elucidates if IDA among 
      healthy women of child bearing age could be predicted by various iron parameters, 
      using serum ferritin as a gold standard. METHODS: Between January and June 2009 
      at primary care clinics of a teaching hospital in Saudi Arabia, 112 anemic 
      (Hemoglobin = 120 g/l) subjects participated in the study. Mean corpuscular 
      volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin 
      concentration (MCHC), red blood cell distribution width (RDW), serum ferritin, 
      and hemoglobin electrophoresis were obtained from all participants. Receiver 
      operator characteristic (ROC) curves were used to assess the accuracy of various 
      iron parameters. RESULTS: With respect to the serum ferritin, the best predictive 
      cut-off value of MCV, MCH and RDW at the most optimal were 76 fl (ROC 
      curve=0.768), 24 Pg (ROC curve=0.72) and 16.1% (ROC curve=0.711), respectively. 
      MCHC was not significant in predicting the iron deficiency in these patients. 
      CONCLUSION: IDA can be predicted among women of child bearing age using complete 
      blood count test. MCV, MCH and RDW are the iron parameters of complete blood 
      count test, which is a cost effective, easily accessible and could be useful tool 
      in areas with limited resources and a high prevalence of the disease.
FAU - Alquaiz, J M
AU  - Alquaiz JM
AD  - Department of Family and Community Medicine, King Khalid University Hospital, 
      King Saud University, College of Medicine, Riyadh, Saudi Arabia ; Chai of 
      Princess Nora for Women's Health Research, King Khalid University Hospital, King 
      Saud University, College of Medicine, Riyadh, Saudi Arabia.
FAU - Abdulghani, H M
AU  - Abdulghani HM
FAU - Khawaja, R A
AU  - Khawaja RA
FAU - Shaffi-Ahamed, S
AU  - Shaffi-Ahamed S
LA  - eng
PT  - Journal Article
DEP - 20120730
PL  - Estonia
TA  - Iran Red Crescent Med J
JT  - Iranian Red Crescent medical journal
JID - 101319850
PMC - PMC3438431
OTO - NOTNLM
OT  - Ferritin
OT  - Iron deficiency anemia
OT  - MCH
OT  - MCV
OT  - RDW
OT  - Women
COIS- Conflict of Interest: None declared.
EDAT- 2012/09/22 06:00
MHDA- 2012/09/22 06:01
PMCR- 2012/07/01
CRDT- 2012/09/22 06:00
PHST- 2011/12/12 00:00 [received]
PHST- 2012/02/20 00:00 [accepted]
PHST- 2012/09/22 06:00 [entrez]
PHST- 2012/09/22 06:00 [pubmed]
PHST- 2012/09/22 06:01 [medline]
PHST- 2012/07/01 00:00 [pmc-release]
PST - ppublish
SO  - Iran Red Crescent Med J. 2012 Jul;14(7):397-401. Epub 2012 Jul 30.