PMID- 22997969
OWN - NLM
STAT- MEDLINE
DCOM- 20121015
LR  - 20191112
IS  - 1433-6510 (Print)
IS  - 1433-6510 (Linking)
VI  - 58
IP  - 7-8
DP  - 2012
TI  - Reference intervals for common biochemical analytes in serum and plasma of a 
      random adult population in the Greater Accra Region of Ghana.
PG  - 687-93
AB  - BACKGROUND: The reference interval (RI) is arguably the most widely used decision 
      making tool in clinical practice. Using the manufacturer's reference values may 
      not be appropriate for other ethnic populations. OBJECTIVE: The objective was to 
      determine the reference intervals (RI) of Ghanaians and compare them to that 
      provided in kits. METHODS: 6300 adults, 25-65 years were selected by cluster 
      sampling from three communities in the Greater Accra Region, Ghana. A total of 
      4733 (male/female ratio = 1:1.5) participated. Fasting Blood Glucose (FF), 2-hour 
      post-glucose plasma glucose (2HPP), total cholesterol (TCHOL), high density 
      lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), 
      triglycerides (TG), uric acid (UA), urea (U), albumin (ALB), alkaline phosphatase 
      (ALP) were measured. RESULTS: Male and female mean ages were 44.9 +/-14.7 and 
      44.0 +/-14.6 years, respectively. Most assays had mean values between the 25th 
      and 75th percentile apart from HDL-C whose mean values fell within the 50th 
      percentile. Thus half of the manufacturers RI (MRI) represented <25 percentile 
      for FF, 2HPP, LDL-C, ALB and ALP. The MRI for Urea was < 25th - > 97.5th. 
      CONCLUSIONS: Mean values of most of the parameters determined represented the 
      25th - 75th and not the 95th or 97.5th percentile.
FAU - Asare, George A
AU  - Asare GA
AD  - Chemical Pathology Unit, Dept. of Med Lab. Sc., School of AlliedHealth Sciences, 
      College of Health Sciences, University of Ghana, P.O. Box KB 143, Korle Bu, 
      Accra, Ghana.
FAU - Ezekiel, N Nortey
AU  - Ezekiel NN
FAU - Nkumpoi, Tabiim
AU  - Nkumpoi T
FAU - Amoah, Albert G B
AU  - Amoah AG
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Clin Lab
JT  - Clinical laboratory
JID - 9705611
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Blood Chemical Analysis
MH  - Female
MH  - Ghana
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Reference Values
EDAT- 2012/09/25 06:00
MHDA- 2012/10/16 06:00
CRDT- 2012/09/25 06:00
PHST- 2012/09/25 06:00 [entrez]
PHST- 2012/09/25 06:00 [pubmed]
PHST- 2012/10/16 06:00 [medline]
AID - 10.7754/clin.lab.2011.110 [doi]
PST - ppublish
SO  - Clin Lab. 2012;58(7-8):687-93. doi: 10.7754/clin.lab.2011.110.