PMID- 22998402
OWN - NLM
STAT- MEDLINE
DCOM- 20130211
LR  - 20220317
IS  - 1547-5646 (Electronic)
IS  - 1547-5646 (Linking)
VI  - 17
IP  - 5
DP  - 2012 Nov
TI  - Changes in the Oswestry Disability Index that predict improvement after lumbar 
      fusion.
PG  - 486-90
LID - 10.3171/2012.8.SPINE12614 [doi]
AB  - OBJECT: Clinical studies use both disease-specific and generic health outcomes 
      measures. Disease-specific measures focus on health domains most relevant to the 
      clinical population, while generic measures assess overall health-related quality 
      of life. There is little information about which domains of the Oswestry 
      Disability Index (ODI) are most important in determining improvement in overall 
      health-related quality of life, as measured by the 36-Item Short Form Health 
      Survey (SF-36), after lumbar spinal fusion. The objective of the study is to 
      determine which clinical elements assessed by the ODI most influence improvement 
      of overall health-related quality of life. METHODS: A single tertiary spine 
      center database was used to identify patients undergoing lumbar fusion for 
      standard degenerative indications. Patients with complete preoperative and 2-year 
      outcomes measures were included. Pearson correlation was used to assess the 
      relationship between improvement in each item of the ODI with improvement in the 
      SF-36 physical component summary (PCS) score, as well as achievement of the SF-36 
      PCS minimum clinically important difference (MCID). Multivariate regression 
      modeling was used to examine which items of the ODI best predicted achievement 
      for the SF-36 PCS MCID. The effect size and standardized response mean were 
      calculated for each of the items of the ODI. RESULTS: A total of 1104 patients 
      met inclusion criteria (674 female and 430 male patients). The mean age at 
      surgery was 57 years. All items of the ODI showed significant correlations with 
      the change in SF-36 PCS score and achievement of MCID for the SF-36 PCS, but only 
      pain intensity, walking, and social life had r values > 0.4 reflecting moderate 
      correlation. These 3 variables were also the dimensions that were independent 
      predictors of the SF-36 PCS, and they were the only dimensions that had effect 
      sizes and standardized response means that were moderate to large. CONCLUSIONS: 
      Of the health dimensions measured by the ODI, pain intensity, walking, and social 
      life best predicted improvement in overall health-related quality of life, as 
      measured using the SF-36 PCS.
FAU - Djurasovic, Mladen
AU  - Djurasovic M
AD  - Norton Leatherman Spine Center, Louisville, Kentucky 40202, USA.
FAU - Glassman, Steven D
AU  - Glassman SD
FAU - Dimar, John R 2nd
AU  - Dimar JR 2nd
FAU - Crawford, Charles H 3rd
AU  - Crawford CH 3rd
FAU - Bratcher, Kelly R
AU  - Bratcher KR
FAU - Carreon, Leah Y
AU  - Carreon LY
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20120921
PL  - United States
TA  - J Neurosurg Spine
JT  - Journal of neurosurgery. Spine
JID - 101223545
SB  - IM
MH  - Activities of Daily Living
MH  - *Disability Evaluation
MH  - Female
MH  - Humans
MH  - Lumbar Vertebrae/*surgery
MH  - Male
MH  - Middle Aged
MH  - Pain Measurement
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Quality of Life
MH  - Recovery of Function
MH  - Regression Analysis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Spinal Fusion/*methods
MH  - Statistics, Nonparametric
MH  - Surveys and Questionnaires
EDAT- 2012/09/25 06:00
MHDA- 2013/02/12 06:00
CRDT- 2012/09/25 06:00
PHST- 2012/09/25 06:00 [entrez]
PHST- 2012/09/25 06:00 [pubmed]
PHST- 2013/02/12 06:00 [medline]
AID - 10.3171/2012.8.SPINE12614 [doi]
PST - ppublish
SO  - J Neurosurg Spine. 2012 Nov;17(5):486-90. doi: 10.3171/2012.8.SPINE12614. Epub 
      2012 Sep 21.