PMID- 22999069 OWN - NLM STAT- MEDLINE DCOM- 20130510 LR - 20220309 IS - 1746-1596 (Electronic) IS - 1746-1596 (Linking) VI - 7 DP - 2012 Sep 21 TI - Primary mesenchymal chondrosarcoma of the kidney with synchronous implant and infiltrating urothelial carcinoma of the ureter. PG - 125 LID - 10.1186/1746-1596-7-125 [doi] AB - Primary mesenchymal chondrosarcoma of the kidney is rare, and it shows distinct undifferentiated tumor cells and well differentiated cartilagenous components. Also assident infiltrating urothelial carcinoma of the ureter is an extremely rare cancer. We report a case of primary mesenchymal chondrosarcoma occurring in the left kidney with an ipsilateral and distinct distal ureteric implant, and a coexisting infiltrating urothelial carcinoma of the ureter in a 64-year-old man. Histopathological examination and immunohistochemical studuies showed the classic features of mesenchymal chondrosarcoma in kidney, as well as a few infiltrating urothelial in ureter. Multitarget fluorescence in situ hybridization (FISH) suggested that the development of the urothelial carcinoma in the ureter may be triggered or induced by the chondrosarcoma component. The patient died 2 month after left nephro-ureterectomy. This is the first reported case of a primary mesenchymal chondrosarcoma of the kidney with coexisting infiltrating urothelial carcinoma of the ureter. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1522835667751019. FAU - Xu, Hua AU - Xu H AD - Departments of Pathology, Shenzhen Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Shenzhen, China. FAU - Shao, MuMin AU - Shao M FAU - Sun, HuiLi AU - Sun H FAU - Li, ShunMin AU - Li S LA - eng PT - Case Reports PT - Journal Article DEP - 20120921 PL - England TA - Diagn Pathol JT - Diagnostic pathology JID - 101251558 RN - 0 (Biomarkers, Tumor) SB - IM MH - Biomarkers, Tumor/analysis/genetics MH - Carcinoma/chemistry/genetics/*pathology/surgery MH - Chondrosarcoma, Mesenchymal/chemistry/genetics/*pathology/surgery MH - Fatal Outcome MH - Humans MH - Immunohistochemistry MH - In Situ Hybridization, Fluorescence MH - Kidney Neoplasms/chemistry/genetics/*pathology/surgery MH - Male MH - Middle Aged MH - Neoplasms, Multiple Primary/chemistry/genetics/*pathology/surgery MH - Nephrectomy MH - Treatment Outcome MH - Ureter/chemistry/*pathology/surgery MH - Ureteral Neoplasms/chemistry/genetics/*pathology/surgery PMC - PMC3533729 EDAT- 2012/09/25 06:00 MHDA- 2013/05/11 06:00 PMCR- 2012/09/21 CRDT- 2012/09/25 06:00 PHST- 2012/06/19 00:00 [received] PHST- 2012/09/17 00:00 [accepted] PHST- 2012/09/25 06:00 [entrez] PHST- 2012/09/25 06:00 [pubmed] PHST- 2013/05/11 06:00 [medline] PHST- 2012/09/21 00:00 [pmc-release] AID - 1746-1596-7-125 [pii] AID - 10.1186/1746-1596-7-125 [doi] PST - epublish SO - Diagn Pathol. 2012 Sep 21;7:125. doi: 10.1186/1746-1596-7-125.