PMID- 22999891
OWN - NLM
STAT- MEDLINE
DCOM- 20130927
LR  - 20220321
IS  - 1573-2517 (Electronic)
IS  - 0165-0327 (Linking)
VI  - 145
IP  - 2
DP  - 2013 Feb 20
TI  - Comorbidity of personality disorders in anxiety disorders: a meta-analysis of 30 
      years of research.
PG  - 143-55
LID - S0165-0327(12)00506-X [pii]
LID - 10.1016/j.jad.2012.07.004 [doi]
AB  - BACKGROUND: A comprehensive meta-analysis to identify the proportions of comorbid 
      personality disorders (PD) across the major subtypes of anxiety disorders (AD) 
      has not previously been published. METHODS: A literature search identified 125 
      empirical papers from the period 1980-2010 on patients with panic disorders, 
      social phobia, generalised anxiety, obsessive-compulsive (OCD) and post-traumatic 
      stress disorder (PTSD). Several moderators were coded. RESULTS: The rate of any 
      comorbid PD was high across all ADs, ranging from .35 for PTSD to .52 for OCD. 
      Cluster C PDs occurred more than twice as often as cluster A or B PDs. Within 
      cluster C the avoidant PD occurred most frequently, followed by the 
      obsessive-compulsive and the dependent PD. PTSD showed the most heterogeneous 
      clinical picture and social phobia was highly comorbid with avoidant PD. A range 
      of moderators were examined, but most were non-significant or of small effects, 
      except an early age of onset, which in social phobia increased the risk of an 
      avoidant PD considerably. Gender or duration of an AD was not related to 
      variation in PD comorbidity. LIMITATIONS: Blind rating of diagnoses was recorded 
      from the papers as an indication of diagnostic validity. However, as too few 
      studies reported it the validity of the comorbid estimates of PD was less strong. 
      CONCLUSIONS: The findings provided support to several of the proposed changes in 
      the forthcoming DSM-5. Further comorbidity studies are needed in view of the 
      substantial changes in how PDs will be diagnosed in the DSM-5.
CI  - Copyright (c) 2012 Elsevier B.V. All rights reserved.
FAU - Friborg, Oddgeir
AU  - Friborg O
AD  - Faculty of Health Sciences, Department of Psychology, University of Tromso, 
      Norway. oddgeir.friborg@uit.no
FAU - Martinussen, Monica
AU  - Martinussen M
FAU - Kaiser, Sabine
AU  - Kaiser S
FAU - Overgard, Karl Tore
AU  - Overgard KT
FAU - Rosenvinge, Jan H
AU  - Rosenvinge JH
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20120921
PL  - Netherlands
TA  - J Affect Disord
JT  - Journal of affective disorders
JID - 7906073
SB  - IM
MH  - Adult
MH  - Anxiety Disorders/*epidemiology
MH  - Comorbidity
MH  - Female
MH  - Humans
MH  - Male
MH  - Obsessive-Compulsive Disorder/epidemiology
MH  - Panic Disorder/epidemiology
MH  - Personality Disorders/*epidemiology
MH  - Phobic Disorders/epidemiology
MH  - Stress Disorders, Post-Traumatic/epidemiology
EDAT- 2012/09/25 06:00
MHDA- 2013/09/28 06:00
CRDT- 2012/09/25 06:00
PHST- 2012/04/24 00:00 [received]
PHST- 2012/07/02 00:00 [revised]
PHST- 2012/07/05 00:00 [accepted]
PHST- 2012/09/25 06:00 [entrez]
PHST- 2012/09/25 06:00 [pubmed]
PHST- 2013/09/28 06:00 [medline]
AID - S0165-0327(12)00506-X [pii]
AID - 10.1016/j.jad.2012.07.004 [doi]
PST - ppublish
SO  - J Affect Disord. 2013 Feb 20;145(2):143-55. doi: 10.1016/j.jad.2012.07.004. Epub 
      2012 Sep 21.