PMID- 23008695
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 1663-2699 (Electronic)
IS  - 1663-2699 (Linking)
VI  - 3
IP  - 1
DP  - 2012 Jan
TI  - Two cases of focal choroidal excavation detected by spectral-domain optical 
      coherence tomography.
PG  - 96-103
AB  - PURPOSE: To report the clinical findings of 2 patients with focal choroidal 
      excavation in the macula detected by spectral-domain optical coherence tomography 
      (SD-OCT). METHODS: Three eyes of 2 patients with a focal macular choroidal 
      excavation detected by SD-OCT were studied. The eyes were examined by fundus 
      autofluorescence (FAF), fluorescein angiography, fundus-related microperimetry, 
      and multifocal electroretinography (mfERG). RESULTS: In spite of a complaint of 
      metamorphopsia, the visual acuity was normal in 2 eyes. SD-OCT demonstrated a 
      choroidal excavation in the macula but the foveal contour was normal in 3 eyes. 
      The excavation involved the outer retinal layers up to the external limiting 
      membrane in all eyes, and a type 2 secondary choroidal neovascularization (CNV) 
      developed in 1 of the 3 eyes. There were areas of hypoautofluorescence in the FAF 
      images, and areas of decreased retinal sensitivity determined by microperimetry. 
      These areas corresponded to the choroidal excavation in all eyes. The P1 
      amplitudes of the mfERGs were decreased in the fovea of 1 eye without a CNV. 
      CONCLUSIONS: The choroidal excavation remained stable for 3 years in 2 eyes, a 
      secondary CNV developed in 1 eye during the course of the disease. More cases and 
      longer follow-up periods will be necessary to determine the etiology, clinical 
      course, and visual prognosis of eyes with a choroidal excavation.
FAU - Katome, Takashi
AU  - Katome T
AD  - Department of Ophthalmology, Institute of Health Biosciences, The University of 
      Tokushima Graduate School, Tokushima, Japan.
FAU - Mitamura, Yoshinori
AU  - Mitamura Y
FAU - Hotta, Fumika
AU  - Hotta F
FAU - Niki, Masanori
AU  - Niki M
FAU - Naito, Takeshi
AU  - Naito T
LA  - eng
PT  - Case Reports
DEP - 20120326
PL  - Switzerland
TA  - Case Rep Ophthalmol
JT  - Case reports in ophthalmology
JID - 101532006
PMC - PMC3448114
OTO - NOTNLM
OT  - Choroidal excavation
OT  - Choroidal neovascularization
OT  - Optical coherence tomography
EDAT- 2012/09/26 06:00
MHDA- 2012/09/26 06:01
PMCR- 2012/03/26
CRDT- 2012/09/26 06:00
PHST- 2012/09/26 06:00 [entrez]
PHST- 2012/09/26 06:00 [pubmed]
PHST- 2012/09/26 06:01 [medline]
PHST- 2012/03/26 00:00 [pmc-release]
AID - cop-0003-0096 [pii]
AID - 10.1159/000337880 [doi]
PST - ppublish
SO  - Case Rep Ophthalmol. 2012 Jan;3(1):96-103. doi: 10.1159/000337880. Epub 2012 Mar 
      26.