PMID- 23010559
OWN - NLM
STAT- MEDLINE
DCOM- 20130514
LR  - 20220408
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 98
IP  - 3
DP  - 2012 Dec
TI  - Risk scores based on self-reported or available clinical data to detect 
      undiagnosed type 2 diabetes: a systematic review.
PG  - 369-85
LID - S0168-8227(12)00309-9 [pii]
LID - 10.1016/j.diabres.2012.09.005 [doi]
AB  - OBJECTIVE: To systematically review published primary research on the development 
      or validation of risk scores that require only self-reported or available 
      clinical data to identify undiagnosed Type 2 Diabetes Mellitus (T2DM). METHODS: A 
      systematic literature search of Medline and EMBASE was conducted until January 
      2011. Studies focusing on the development or validation of risk scores to 
      identify undiagnosed T2DM were included. Risk scores to predict future risk of 
      T2DM were excluded. RESULTS: Thirty-one studies were included; 17 developed a new 
      risk score, 14 validated existing scores. Twenty-six studies were conducted in 
      high-income countries. Age and measures of body mass/fat distribution were the 
      most commonly used predictor variables. Studies developing new scores performed 
      better than validation studies, with 11 reporting an AUC of >0.80 compared to one 
      validation study. Fourteen validation studies reported sensitivities of <80%. The 
      performance of scores did not differ by the number of variables included or the 
      country setting. CONCLUSIONS: There is a proliferation of newly developed risk 
      scores using similar variables, which sometimes perform poorly upon external 
      validation. Future research should explore the recalibration, validation and 
      applicability of existing scores to other settings, particularly in low/middle 
      income countries, and on the utility of scores to improve diabetes-related 
      outcomes.
CI  - Copyright (c) 2012 Elsevier Ireland Ltd. All rights reserved.
FAU - Brown, Nicola
AU  - Brown N
AD  - Asia Diabetes Foundation, Hong Kong, China. nicola.brown26@hotmail.co.uk
FAU - Critchley, Julia
AU  - Critchley J
FAU - Bogowicz, Paul
AU  - Bogowicz P
FAU - Mayige, Mary
AU  - Mayige M
FAU - Unwin, Nigel
AU  - Unwin N
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20120923
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Adiposity
MH  - Age Factors
MH  - Body Mass Index
MH  - Diabetes Mellitus, Type 2/*diagnosis/epidemiology
MH  - Evidence-Based Medicine
MH  - Humans
MH  - Mass Screening/*methods
MH  - Risk
MH  - Self Report
EDAT- 2012/09/27 06:00
MHDA- 2013/05/15 06:00
CRDT- 2012/09/27 06:00
PHST- 2012/03/05 00:00 [received]
PHST- 2012/06/19 00:00 [revised]
PHST- 2012/09/04 00:00 [accepted]
PHST- 2012/09/27 06:00 [entrez]
PHST- 2012/09/27 06:00 [pubmed]
PHST- 2013/05/15 06:00 [medline]
AID - S0168-8227(12)00309-9 [pii]
AID - 10.1016/j.diabres.2012.09.005 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2012 Dec;98(3):369-85. doi: 
      10.1016/j.diabres.2012.09.005. Epub 2012 Sep 23.