PMID- 2301349 OWN - NLM STAT- MEDLINE DCOM- 19900315 LR - 20190510 IS - 0002-9262 (Print) IS - 0002-9262 (Linking) VI - 131 IP - 3 DP - 1990 Mar TI - Sex ratio of human T-lymphotropic virus type I infection and blood transfusion. PG - 395-9 AB - The prevalence of human T-lymphotropic virus type I (HTLV-I) infection is higher for females than for males. Blood transfusion is a potential confounding factor which might contribute to this high female:male ratio. Two studies were performed in Martinique (French West Indies) to clarify this issue: a case-control survey comparing the experience of previous blood transfusion among 62 HTLV-I-seropositive and 88 HTLV-I-seronegative blood donors, and a retrospective study of the sex of recipients of blood. Blood transfusion was strongly associated with HTLV-I infection (odds ratio = 6.4, p less than 0.001). Females were more often given blood transfusions (57.9 percent, p less than 0.001) and received a higher percentage of blood units (53.5 percent, p less than 0.05) than could be expected from their proportion in the general population (51.6 percent). Thus, the high female:male sex ratio of HTLV-I-infected subjects might be due partially to a sex difference for blood transfusion. FAU - Chavance, M AU - Chavance M AD - INSERM U169, Villejuif, France. FAU - Frery, N AU - Frery N FAU - Valette, I AU - Valette I FAU - Schaffar-Deshayes, L AU - Schaffar-Deshayes L FAU - Monplaisir, N AU - Monplaisir N LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Am J Epidemiol JT - American journal of epidemiology JID - 7910653 SB - IM MH - Adult MH - Case-Control Studies MH - Female MH - HTLV-I Infections/epidemiology/*etiology MH - Humans MH - Male MH - Martinique/ethnology MH - Middle Aged MH - Retrospective Studies MH - Risk Factors MH - Sex Factors MH - *Transfusion Reaction EDAT- 1990/03/01 00:00 MHDA- 1990/03/01 00:01 CRDT- 1990/03/01 00:00 PHST- 1990/03/01 00:00 [pubmed] PHST- 1990/03/01 00:01 [medline] PHST- 1990/03/01 00:00 [entrez] AID - 10.1093/oxfordjournals.aje.a115514 [doi] PST - ppublish SO - Am J Epidemiol. 1990 Mar;131(3):395-9. doi: 10.1093/oxfordjournals.aje.a115514.