PMID- 23024482
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 0974-0422 (Electronic)
IS  - 0970-1915 (Print)
IS  - 0970-1915 (Linking)
VI  - 26
IP  - 4
DP  - 2011 Oct
TI  - A Case of Light Chain Deposition Disease (LCDD) in a Young Patient.
PG  - 420-2
AB  - Light chain disease is a variant of multiple myeloma in which the malignant 
      population of marrow cells produces free monoclonal light chains but no heavy 
      chain or complete immunoglobulin. The monoclonal light chains are small enough to 
      be freely filtered by the kidneys and become Bence-Jones protein. Light chain 
      disease comprises about 18% of multiple myeloma patients. Here we present a case 
      report of a 38-year-old man who initially presented with complaints of pain in 
      back and low grade fever off and on. He was found to have collapse of D9 and D12 
      vertebrae along with ascites and right pleural effusion and massive proteinuria. 
      Multiple myeloma was considered as a differential diagnosis based on the 
      investigations but eventually the patient was lost to follow up. This case is 
      reported here as the light chain variant of multiple myeloma leading to 
      deposition disease is less commonly reported and presents considerable 
      difficulties in diagnosis.
FAU - Mahto, Mala
AU  - Mahto M
AD  - Department of Biochemistry, Maulana Azad Medical College, New Delhi, 110002 
      India.
FAU - Mohapatra, Sudhesna
AU  - Mohapatra S
FAU - Sumitra, G
AU  - Sumitra G
FAU - Kaushik, Smita
AU  - Kaushik S
FAU - Mishra, T K
AU  - Mishra TK
FAU - Saxena, Alpana
AU  - Saxena A
LA  - eng
PT  - Case Reports
DEP - 20110111
PL  - India
TA  - Indian J Clin Biochem
JT  - Indian journal of clinical biochemistry : IJCB
JID - 8708303
PMC - PMC3210242
OTO - NOTNLM
OT  - Bence-Jones protein
OT  - Light chain disease
OT  - Multiple myeloma
EDAT- 2012/10/02 06:00
MHDA- 2012/10/02 06:01
PMCR- 2012/10/01
CRDT- 2012/10/02 06:00
PHST- 2010/11/14 00:00 [received]
PHST- 2010/12/28 00:00 [accepted]
PHST- 2012/10/02 06:00 [entrez]
PHST- 2012/10/02 06:00 [pubmed]
PHST- 2012/10/02 06:01 [medline]
PHST- 2012/10/01 00:00 [pmc-release]
AID - 105 [pii]
AID - 10.1007/s12291-010-0105-z [doi]
PST - ppublish
SO  - Indian J Clin Biochem. 2011 Oct;26(4):420-2. doi: 10.1007/s12291-010-0105-z. Epub 
      2011 Jan 11.