PMID- 23027103 OWN - NLM STAT- MEDLINE DCOM- 20130305 LR - 20131121 IS - 1537-1603 (Electronic) IS - 0736-0258 (Linking) VI - 29 IP - 5 DP - 2012 Oct TI - Comparison of triphasic waves and epileptic discharges in one patient with genetic epilepsy. PG - 458-61 LID - 10.1097/WNP.0b013e31826bde70 [doi] AB - Genetic epilepsies with generalized spike-wave complexes (GSWCs) and encephalopathy triphasic waves (TWs) may resemble each other and have three phases per complex. Electroencephalographic (EEG) interpretation is subjective, and EEGers have noted "TWs" in cases labeled nonconvulsive status epilepticus (NCSE). Direct comparison of both wave forms under the same conditions is rarely possible. In a single patient with generalized spike waves who developed hepatic TWs, morphologic characteristics of both were compared, and it was found that GSWCs have higher frequency first, second, and third phases; steeper phase 2 slope; and briefer after-going slow waves maximal at F3 to F4. Total complex duration was approximately 0.12 seconds. The TWs had dominant high-voltage phases 2 and 3 located more posteriorly, in the frontocentral region, lasting an average of approximately 0.32 seconds. These morphologic distinctions may help differentiate TWs from GSWCs. FAU - Kaplan, Peter W AU - Kaplan PW AD - Johns Hopkins University School of Medicine, Baltimore, MD, USA. pkaplan@jhmi.edu FAU - Schlattman, Dan K AU - Schlattman DK LA - eng PT - Case Reports PT - Comparative Study PT - Journal Article PL - United States TA - J Clin Neurophysiol JT - Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society JID - 8506708 RN - 0 (Anticonvulsants) RN - 614OI1Z5WI (Valproic Acid) SB - IM CIN - J Clin Neurophysiol. 2013 Apr;30(2):210-1. PMID: 23545775 MH - Anticonvulsants/administration & dosage MH - Brain/drug effects/*physiopathology MH - Brain Mapping/*methods MH - *Brain Waves/drug effects/genetics MH - Diagnosis, Differential MH - *Electroencephalography MH - Epilepsy, Generalized/*diagnosis/drug therapy/genetics/physiopathology MH - Genetic Predisposition to Disease MH - Humans MH - Male MH - Middle Aged MH - Periodicity MH - Phenotype MH - Predictive Value of Tests MH - Status Epilepticus/*diagnosis/drug therapy/genetics/physiopathology MH - Time Factors MH - Valproic Acid/administration & dosage EDAT- 2012/10/03 06:00 MHDA- 2013/03/06 06:00 CRDT- 2012/10/03 06:00 PHST- 2012/10/03 06:00 [entrez] PHST- 2012/10/03 06:00 [pubmed] PHST- 2013/03/06 06:00 [medline] AID - 00004691-201210000-00014 [pii] AID - 10.1097/WNP.0b013e31826bde70 [doi] PST - ppublish SO - J Clin Neurophysiol. 2012 Oct;29(5):458-61. doi: 10.1097/WNP.0b013e31826bde70.