PMID- 23028178
OWN - NLM
STAT- MEDLINE
DCOM- 20131125
LR  - 20130830
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 64
IP  - 7
DP  - 2013 Oct
TI  - Mean platelet volume and extent and complexity of coronary artery disease in 
      diabetic and nondiabetic patients with ST elevation myocardial infarction.
PG  - 505-11
LID - 10.1177/0003319712460423 [doi]
AB  - We investigated whether the mean platelet volume (MPV) is associated with the 
      extent and complexity of coronary artery disease in patients with ST elevation 
      myocardial infarction (STEMI). We prospectively included 912 STEMI patients (663 
      male and 249 female; mean age 58.7 +/- 12.4 years) who underwent primary 
      percutaneous coronary intervention. The patients were divided into 3 groups 
      according to MPV tertiles. Highest SYNTAX score (SS) was observed in MPVhigh 
      group compared with MPVmid and MPVlow groups (P < .001 for all). The SS of MPVmid 
      group was higher than MPVlow group (P = .036). The MPV in diabetic STEMI patients 
      was higher than in nondiabetic STEMI patients (P < .001). Multivariate linear 
      regression analysis showed that the MPV was associated with diabetes (beta = .115, P 
      = .001), troponin level (beta = .131, P = .001), platelet count (beta = -.241, P < 
      .001), and SS (beta = .216, P < .001). The relation between MPV and SS in diabetic 
      STEMI patients was stronger than for nondiabetic STEMI patients (r = .473, P < 
      .001 vs r = .129, P = .001).
FAU - Sahin, Durmus Yildiray
AU  - Sahin DY
AD  - Department of Cardiology, Adana Numune Education and Research Hospital, Adana, 
      Turkey. dysahin79@hotmail.com
FAU - Gur, Mustafa
AU  - Gur M
FAU - Elbasan, Zafer
AU  - Elbasan Z
FAU - Ozdogru, Ibrahim
AU  - Ozdogru I
FAU - Uysal, Onur Kadir
AU  - Uysal OK
FAU - Kivrak, Ali
AU  - Kivrak A
FAU - Gozubuyuk, Gokhan
AU  - Gozubuyuk G
FAU - Turkoglu, Caner
AU  - Turkoglu C
FAU - Ozkan, Bugra
AU  - Ozkan B
FAU - Cayli, Murat
AU  - Cayli M
LA  - eng
PT  - Journal Article
DEP - 20121001
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Platelets/*pathology
MH  - *Cell Size
MH  - Coronary Angiography
MH  - Coronary Artery Disease/*blood/surgery
MH  - Diabetes Mellitus/*blood
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*blood
MH  - Platelet Count
MH  - Prospective Studies
OTO - NOTNLM
OT  - SYNTAX score
OT  - diabetes
OT  - mean platelet volume
OT  - myocardial infarction
EDAT- 2012/10/03 06:00
MHDA- 2013/12/16 06:00
CRDT- 2012/10/03 06:00
PHST- 2012/10/03 06:00 [entrez]
PHST- 2012/10/03 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 0003319712460423 [pii]
AID - 10.1177/0003319712460423 [doi]
PST - ppublish
SO  - Angiology. 2013 Oct;64(7):505-11. doi: 10.1177/0003319712460423. Epub 2012 Oct 1.