PMID- 23030242
OWN - NLM
STAT- MEDLINE
DCOM- 20140326
LR  - 20130730
IS  - 1943-3670 (Electronic)
IS  - 0022-3492 (Linking)
VI  - 84
IP  - 8
DP  - 2013 Aug
TI  - The sociodemographic characteristics, periodontal health status, and subgingival 
      microbiota of patients with chronic periodontitis and type 2 diabetes mellitus: a 
      case-control study in a Chinese population.
PG  - 1058-66
LID - 10.1902/jop.2012.120282 [doi]
AB  - BACKGROUND: In China, chronic periodontitis (CP) is common in patients with type 
      2 diabetes mellitus (T2DM). The purpose of this study is to identify the 
      sociodemographic characteristics associated with such patients and to assess the 
      periodontal health status and subgingival microbiota of patients with CP and T2DM 
      (T2DMCP) in the Chinese population. METHODS: A total of 150 patients with T2DMCP 
      and 306 patients with CP without any systemic disease completed questionnaires, 
      underwent clinical periodontal examinations and participated in diabetes-related 
      parameter examinations. Subgingival plaques were obtained to determine the 
      prevalence and amounts of selected oral bacterial species using polymerase chain 
      reaction (PCR) and real-time PCR, respectively. RESULTS: The income level and 
      mean body mass index (BMI) of the patients with T2DMCP were significantly higher 
      than those of the patients with CP. Additionally, the patients with T2DMCP were 
      more likely to be urban residents, and they had significantly more severe 
      periodontitis than did the patients with CP. In the patients with T2DMCP, the 
      prevalence and amounts of Treponema denticola and Tannerella forsythia were 
      significantly higher than those in the patients with CP. Finally, compared with 
      the patients with CP, the patients with T2DMCP had a significantly lower 
      prevalence and amount of Prevotella intermedia. CONCLUSIONS: Compared with the 
      patients with CP, the patients with T2DMCP were more likely to be urban residents 
      and generally had higher incomes, higher mean BMI, and poorer periodontal health 
      status. Higher levels of T. denticola and T. forsythia and lower levels of P. 
      intermedia were identified in the subgingival plaque of the patients with T2DMCP.
FAU - Li, Chen
AU  - Li C
AD  - Department of Periodontics, School of Stomatology, China Medical University, 
      Shenyang, Liaoning, China.
FAU - Liu, Jingbo
AU  - Liu J
FAU - Tan, Lisi
AU  - Tan L
FAU - Yu, Ning
AU  - Yu N
FAU - Lin, Li
AU  - Lin L
FAU - Geng, Fengxue
AU  - Geng F
FAU - Zhang, Dongmei
AU  - Zhang D
FAU - Pan, Yaping
AU  - Pan Y
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121002
PL  - United States
TA  - J Periodontol
JT  - Journal of periodontology
JID - 8000345
RN  - 0 (Blood Glucose)
RN  - 0 (DNA, Bacterial)
SB  - IM
MH  - Alveolar Bone Loss/complications/microbiology
MH  - Bacterial Load
MH  - Bacteroides/isolation & purification
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - Case-Control Studies
MH  - China
MH  - Chronic Periodontitis/complications/*microbiology/therapy
MH  - DNA, Bacterial/analysis
MH  - Dental Plaque/microbiology
MH  - Diabetes Mellitus, Type 2/complications/*microbiology/prevention & control
MH  - Educational Status
MH  - Female
MH  - Gingiva/*microbiology
MH  - Gram-Negative Bacteria/*isolation & purification
MH  - Health Status
MH  - Humans
MH  - Income
MH  - Male
MH  - Middle Aged
MH  - *Periodontal Index
MH  - Polymerase Chain Reaction
MH  - Prevotella intermedia/isolation & purification
MH  - Rural Health
MH  - Smoking
MH  - Socioeconomic Factors
MH  - Treponema denticola/isolation & purification
MH  - Urban Health
EDAT- 2012/10/04 06:00
MHDA- 2014/03/29 06:00
CRDT- 2012/10/04 06:00
PHST- 2012/10/04 06:00 [entrez]
PHST- 2012/10/04 06:00 [pubmed]
PHST- 2014/03/29 06:00 [medline]
AID - 10.1902/jop.2012.120282 [doi]
PST - ppublish
SO  - J Periodontol. 2013 Aug;84(8):1058-66. doi: 10.1902/jop.2012.120282. Epub 2012 
      Oct 2.