PMID- 23051124
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121210
LR  - 20160519
IS  - 1876-2026 (Electronic)
IS  - 1876-2018 (Linking)
VI  - 4
IP  - 3
DP  - 2011 Sep
TI  - A case series of lamotrigine increased to 300mg daily in patients with bipolar 
      depression.
PG  - 223
LID - 10.1016/j.ajp.2011.05.007 [doi]
AB  - Bipolar depression is a condition lacking sufficient treatment options. While 
      lamotrigine appears effective, clinical trials and prescribing guidelines address 
      only daily doses below 300mg. METHODOLOGY: Thirteen consecutive outpatients with 
      bipolar depression and taking 200mg of daily lamotrigine were openly administered 
      a dose increased to 300mg and naturalistically followed. Study outcome was 
      assessed by comparison of pre- and post-treatment Beck Depression Inventory (BDI) 
      and Global Assessment of Functioning (GAF) scores. Stastical analysis applied the 
      paired t-test. RESULTS: Increasing daily lamotrigine dose to 300mg was associated 
      with good tolerability and significant improvement in BDI and GAF scores.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Abraham, Praveen Francis
AU  - Abraham PF
AD  - Nord Center, 6140 South Broadway, Lorain, Ohio, OH, USA.
LA  - eng
PT  - Letter
DEP - 20110830
PL  - Netherlands
TA  - Asian J Psychiatr
JT  - Asian journal of psychiatry
JID - 101517820
EDAT- 2012/10/12 06:00
MHDA- 2012/10/12 06:01
CRDT- 2012/10/12 06:00
PHST- 2011/01/09 00:00 [received]
PHST- 2011/05/01 00:00 [revised]
PHST- 2011/05/15 00:00 [accepted]
PHST- 2012/10/12 06:00 [entrez]
PHST- 2012/10/12 06:00 [pubmed]
PHST- 2012/10/12 06:01 [medline]
AID - S1876-2018(11)00052-9 [pii]
AID - 10.1016/j.ajp.2011.05.007 [doi]
PST - ppublish
SO  - Asian J Psychiatr. 2011 Sep;4(3):223. doi: 10.1016/j.ajp.2011.05.007. Epub 2011 
      Aug 30.