PMID- 23052930
OWN - NLM
STAT- MEDLINE
DCOM- 20130925
LR  - 20211021
IS  - 1433-2965 (Electronic)
IS  - 0937-941X (Linking)
VI  - 24
IP  - 4
DP  - 2013 Apr
TI  - Efficacy of home-based virtual cycling training on bone mineral density in 
      ambulatory children with cerebral palsy.
PG  - 1399-406
LID - 10.1007/s00198-012-2137-0 [doi]
AB  - The 12-week home-based virtual cycling training (hVCT) improved lower limb muscle 
      strength and areal bone mineral density (aBMD) than the control program in 
      children with cerebral palsy (CP). A muscle strengthening program, rather than 
      general physical activity, is more specific in enhancing aBMD for these children. 
      A novel hVCT is an effective and efficient strategy that enhances lower limb bone 
      density in these children. INTRODUCTION: This is the first study to assess the 
      efficacy of a novel hVCT program on bone density for children with spastic CP 
      using a well-designed randomized controlled trial. METHODS: Twenty-seven 
      ambulatory children with spastic CP, aged 6-12 years, were randomly assigned to 
      the hVCT group (n=13) or control group (n=14). Outcome measures-motor function 
      [Gross Motor Function Measure-66 (GMFM-66)], muscle strength (curl up scores and 
      isokinetic torque of knee extensor and flexor muscle) and aBMD of the lumbar and 
      distal femur-were administered before and immediately after the 12-week 
      intervention. RESULTS: Analysis of covariance results show that the hVCT group 
      had greater distal femur aBMD and isokinetic torques of knee extensor and flexor 
      muscles than the control group at posttreatment (p<0.05). However, curl up 
      scores, GMFM-66, and lumbar aBMD at posttreatment did not differ between the two 
      groups. CONCLUSIONS: Analytical findings suggest that the muscle strengthening 
      program is more specific in enhancing bone density for children with CP than 
      general physical activity. Thus, the proposed 12-week hVCT protocol is an 
      effective and efficient strategy for improving lower limb aBMD in these children.
FAU - Chen, C-L
AU  - Chen CL
AD  - Physical Medicine and Rehabilitation, Chang Gung Memorial hospital, Linkou, and 
      Graduate Institute of Early Intervention, College of Medicine, Chang Gung 
      University, 5 Fu-Hsing St. Kwei-Shan, Tao-Yuan, 333, Taiwan.
FAU - Chen, C-Y
AU  - Chen CY
FAU - Liaw, M-Y
AU  - Liaw MY
FAU - Chung, C-Y
AU  - Chung CY
FAU - Wang, C-J
AU  - Wang CJ
FAU - Hong, W-H
AU  - Hong WH
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20120928
PL  - England
TA  - Osteoporos Int
JT  - Osteoporosis international : a journal established as result of cooperation 
      between the European Foundation for Osteoporosis and the National Osteoporosis 
      Foundation of the USA
JID - 9100105
SB  - IM
MH  - Bicycling/*physiology
MH  - Bone Density/*physiology
MH  - Cerebral Palsy/physiopathology/*rehabilitation
MH  - Child
MH  - Exercise Therapy/*methods
MH  - Female
MH  - Femur/physiopathology
MH  - *Home Care Services
MH  - Humans
MH  - Knee Joint/physiopathology
MH  - Male
MH  - Muscle Strength/physiology
MH  - Muscle, Skeletal/physiopathology
MH  - Range of Motion, Articular/physiology
MH  - Treatment Outcome
MH  - Virtual Reality Exposure Therapy/*methods
MH  - Walking/physiology
EDAT- 2012/10/12 06:00
MHDA- 2013/09/26 06:00
CRDT- 2012/10/12 06:00
PHST- 2011/12/03 00:00 [received]
PHST- 2012/08/07 00:00 [accepted]
PHST- 2012/10/12 06:00 [entrez]
PHST- 2012/10/12 06:00 [pubmed]
PHST- 2013/09/26 06:00 [medline]
AID - 10.1007/s00198-012-2137-0 [doi]
PST - ppublish
SO  - Osteoporos Int. 2013 Apr;24(4):1399-406. doi: 10.1007/s00198-012-2137-0. Epub 
      2012 Sep 28.