PMID- 23054574
OWN - NLM
STAT- MEDLINE
DCOM- 20130820
LR  - 20221207
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 23
IP  - 2
DP  - 2013 Feb
TI  - Type 2 diabetes mellitus in patients with mild obesity: preliminary results of 
      surgical treatment.
PG  - 234-40
LID - 10.1007/s11695-012-0780-3 [doi]
AB  - In the last years, type 2 diabetes mellitus (T2DM) and obesity have become a 
      serious public health problem, behaving as epidemic diseases. There is great 
      interest in exploring different options for the treatment of T2DM in nonmorbidly 
      obese patients. The purpose of this study is to report parameters of glycemic 
      control in patients with T2DM and mild obesity who underwent laparoscopic 
      Roux-en-Y gastric bypass (RYGBP). This prospective clinical trial includes 
      patients with T2DM with a body mass index (BMI) between 30 and 35 kg/m(2) who 
      underwent laparoscopic RYGBP from July 2008 through October 2010. Thirty-one 
      patients were included in the study, 15 men and 16 women, with an average age of 
      48.7 +/- 8.6 years. The average time since onset of T2DM was 5.8 years. The average 
      postoperative follow-up was 30.4 months. The average preoperative blood glucose 
      and glycosylated hemoglobin were 152 +/- 70 mg/dl and 7.7 +/- 2.1 %, respectively. 
      All of them were using oral hypoglycemic agents, and four patients were insulin 
      dependent. Only one patient had a postoperative complication (hemoperitoneum). At 
      36 months follow-up, the average BMI decreased to 24.7 kg/m(2), all patients (31) 
      showed improvement in their glycemic control, and 29 of them (93.6 %) met the 
      criteria for remission of T2DM in the last control. Laparoscopic RYGBP is a safe 
      and effective procedure that improves glycemic control in patients with T2DM and 
      mild obesity at midterm follow-up.
FAU - Lanzarini, Enrique
AU  - Lanzarini E
AD  - Department of Surgery, Hospital J.J. Aguirre, University Hospital, Santos Dumont 
      999, Santiago, Chile. elanzarini@hotmail.com
FAU - Csendes, Attila
AU  - Csendes A
FAU - Gutierrez, Luis
AU  - Gutierrez L
FAU - Cuevas, Pedro
AU  - Cuevas P
FAU - Lembach, Hanns
AU  - Lembach H
FAU - Molina, Juan C
AU  - Molina JC
FAU - Musleh, Maher
AU  - Musleh M
FAU - Braghetto, Italo
AU  - Braghetto I
FAU - Papapietro, Karin
AU  - Papapietro K
FAU - Araya, Veronica
AU  - Araya V
FAU - Lahsen, Rodolfo
AU  - Lahsen R
FAU - Olguin, Pablo
AU  - Olguin P
FAU - Riffo, Andrea
AU  - Riffo A
FAU - Diaz, Emma
AU  - Diaz E
FAU - Montt, Denisse
AU  - Montt D
FAU - Marin, Luciana
AU  - Marin L
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Blood Glucose/metabolism
MH  - Body Mass Index
MH  - Diabetes Mellitus, Type 2/*blood/physiopathology
MH  - Female
MH  - Follow-Up Studies
MH  - Gastric Bypass/*methods
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Obesity/blood/physiopathology/*surgery
MH  - Prospective Studies
MH  - Remission Induction
MH  - Treatment Outcome
MH  - Weight Loss
EDAT- 2012/10/12 06:00
MHDA- 2013/08/21 06:00
CRDT- 2012/10/12 06:00
PHST- 2012/10/12 06:00 [entrez]
PHST- 2012/10/12 06:00 [pubmed]
PHST- 2013/08/21 06:00 [medline]
AID - 10.1007/s11695-012-0780-3 [doi]
PST - ppublish
SO  - Obes Surg. 2013 Feb;23(2):234-40. doi: 10.1007/s11695-012-0780-3.