PMID- 23061304
OWN - NLM
STAT- MEDLINE
DCOM- 20121204
LR  - 20221207
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 95
IP  - 8
DP  - 2012 Aug
TI  - Prevalence of factors predisposing to foot complication and their relation to 
      other risks.
PG  - 1013-20
AB  - BACKGROUND: Diabetic neuropathy and peripheral vascular disease (PVD) have been 
      identified as major risk factors for diabetic foot ulceration and amputation in 
      patients with type 2 diabetes mellitus (T2DM) but in Thailand have been a few of 
      prospective studied about the prevalence and risk factors of diabetic neuropathy 
      and PVD. OBJECTIVE: To evaluate the prevalence of diabetic neuropathy and PVD in 
      Thai patients with T2DM and to determine other factors that related with them. 
      MATERIAL AND METHOD: A cross-sectional study of 899 Thai T2DM patients from the 
      out-patient department of seven public hospitals in Thailand between January 2007 
      and September 2008 was performed. Histories of these patients, complete physical 
      examinations, feet examination, and blood with urine chemistry were obtained. 
      RESULTS: Most of the patients were females with the average age of 59.64 years, 
      the average of body mass index (BMI) was 27.32 kg/m2, the average duration of 
      diabetes was 8.12 years and 85.17% of patients were HbA1C > or = 7%. Diabetic 
      patients with PVD group compared with no PVD group, there were statistically 
      significant differences for duration of having diabetes (OR 1.08; 95% CI 
      [1.01-1.16]; p-value 0.047), creatinine level (OR 1.62; 95% CI [1.12-2.33]; 
      p-value 0.01), present diabetic neuropathy (OR, 7.37; 95% CI [2.52-21.59]; 
      p-value < 0.001). Patients with diabetic neuropathy group compared with no 
      diabetic neuropathy group, there were statistically significant differences of 
      age (OR, 1.04; 95% CI [1.01-1.06]; p-value 0.003), duration of having diabetes 
      (OR, 1.04; 95% CI [1.01-1.07]; p-value 0.008), on ACEI or ARB drug (OR, 1.77; 95% 
      CI [1.24-2.55]; p-value 0.002), HbA1C (OR, 1.14; 95% CI [1.03-1.27]; p-value 
      0.012), creatinine level (OR, 1.38; 95% CI [1.04-1.79]; p-value 0.014), present 
      diabetic retinopathy (OR, 1.96; 95% CI [1.22-3.13]; p-value 0.005), present PVD 
      (OR, 7.37; 95% CI [2.52-21.59]; p-value < 0.001), present diabetic nephropathy 
      with microalbuminuria (OR, 1.74; 95% CI [1.12-2.69]; p-value 0.013). CONCLUSION: 
      Two percent of T2DM patients had PVD that associated with duration of diabetes, 
      creatinine level, and diabetic neuropathy and 15% of T2DM patients had diabetic 
      neuropathy that depended on age, duration of having diabetes, on ACEI or ARB 
      drug, creatinine level, HbA1C, diabetic retinopathy, diabetic nephropathy, and 
      PVD.
FAU - Sattaputh, Charnvate
AU  - Sattaputh C
AD  - Department of Surgery, Lerdsin Hospital, Ministry of Public Health, Bangkok, 
      Thailand. scorpionpon2@hotmail.com
FAU - Potisat, Somkiat
AU  - Potisat S
FAU - Jongsareejit, Amporn
AU  - Jongsareejit A
FAU - Krairittichai, Udom
AU  - Krairittichai U
FAU - Pooreesathian, Kunakorn
AU  - Pooreesathian K
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Age Factors
MH  - Creatinine/analysis
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Diabetic Neuropathies/*epidemiology
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Peripheral Vascular Diseases/*epidemiology
MH  - Thailand/epidemiology
MH  - Time Factors
EDAT- 2012/10/16 06:00
MHDA- 2012/12/10 06:00
CRDT- 2012/10/16 06:00
PHST- 2012/10/16 06:00 [entrez]
PHST- 2012/10/16 06:00 [pubmed]
PHST- 2012/12/10 06:00 [medline]
PST - ppublish
SO  - J Med Assoc Thai. 2012 Aug;95(8):1013-20.