PMID- 23061710 OWN - NLM STAT- MEDLINE DCOM- 20130423 LR - 20220317 IS - 1747-4132 (Electronic) IS - 1747-4124 (Linking) VI - 6 IP - 5 DP - 2012 Sep TI - Eosinophilic gastroenteritis: an update. PG - 591-601 LID - 10.1586/egh.12.42 [doi] AB - Eosinophilic gastroenteritis (EGE) is characterized by dense eosinophilic inflammation of one or several digestive tract sections. The symptoms include abdominal pain, weight loss, vomiting and diarrhea. Biopsy samples taken during endoscopic examination allows the diagnosis of the disease. An infiltration of >30 eosinophils per high-power field in at least five high-power fields, exhibiting signs of eosinophilic degranulation and extending to the muscularis mucosa or submucosa are all histological indications of EGE. EGE is traditionally classified into three forms depending on the depth of inflammation in the wall (mucosal, muscular or serosal). This, together with the digestive tract segments involved, determines the clinical presentation. The natural history of EGE includes three different evolutionary patterns, since patients may suffer a single outbreak, a recurrent course or even chronic disease. Corticosteroids are the most frequently used therapy for EGE; dietary treatments should be also considered. Surgery has been limited to solving obstruction and small bowel perforation. FAU - Lucendo, Alfredo J AU - Lucendo AJ AD - Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Ciudad Real, Spain. alucendo@vodafone.es FAU - Arias, Angel AU - Arias A LA - eng PT - Journal Article PT - Review PL - England TA - Expert Rev Gastroenterol Hepatol JT - Expert review of gastroenterology & hepatology JID - 101278199 RN - Eosinophilic enteropathy SB - IM MH - Enteritis/complications/epidemiology/*physiopathology/therapy MH - Eosinophilia/complications/epidemiology/*physiopathology/therapy MH - Gastritis/complications/epidemiology/*physiopathology/therapy MH - Humans EDAT- 2012/10/16 06:00 MHDA- 2013/04/24 06:00 CRDT- 2012/10/16 06:00 PHST- 2012/10/16 06:00 [entrez] PHST- 2012/10/16 06:00 [pubmed] PHST- 2013/04/24 06:00 [medline] AID - 10.1586/egh.12.42 [doi] PST - ppublish SO - Expert Rev Gastroenterol Hepatol. 2012 Sep;6(5):591-601. doi: 10.1586/egh.12.42.