PMID- 23065096 OWN - NLM STAT- MEDLINE DCOM- 20131216 LR - 20211021 IS - 1875-8312 (Electronic) IS - 1569-5794 (Linking) VI - 29 IP - 4 DP - 2013 Apr TI - Unrestricted utilization of frequency domain optical coherence tomography in coronary interventions. PG - 741-52 LID - 10.1007/s10554-012-0135-0 [doi] AB - Frequency domain optical coherence tomography (FD-OCT) has shown promise to evaluate coronary devices in clinical trials, however, little is known about its application in clinical practice. This prospective, single center initiative planned for 100 % FD-OCT utilization in all patients undergoing coronary interventions during a 60-day period. Operators pre-specified the planned intervention based on angiography alone. FD-OCT success was defined as acquisition of good quality images enabling adequate quantification of vessel dimensions and lesion/percutaneous coronary intervention (PCI) assessment. Impact on management occurred when angiography-based planning was altered based on FD-OCT data. There were 297 FD-OCT acquisitions performed in 155 vessels from 150 patients. There were no FD-OCT procedural related cardiac adverse events and success was obtained in 85.7 % of all target vessels (pre-PCI = 76.8 % vs. post-PCI = 90.1 %, p = 0.004). Success on the first pullback occurred in 80.3 % overall (61.9 % in the initial operator experience and 85.5 % after the third procedure). FD-OCT impact on management was 81.8 % pre-PCI and 54.8 % post-PCI. Stent malapposition was detected in 39.2 % (89.4 % underwent further intervention) and edge dissection in 32.5 % (21.1 % treated with stent). FD-OCT success and management impact were similar in ACS and non-ACS patients (82.1 vs. 81.1 %, p = 1.000, and 62.5 vs. 65.1 %, p = 0.854, respectively). FD-OCT is safe, can successfully be incorporated into routine practice, and alters procedural strategy in a high proportion of patients undergoing PCI. FAU - Stefano, Gregory T AU - Stefano GT AD - Harrington-McLaughlin Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Lakeside 3001, Cleveland, OH 44106-5038, USA. FAU - Bezerra, Hiram G AU - Bezerra HG FAU - Mehanna, Emile AU - Mehanna E FAU - Yamamoto, Hirosada AU - Yamamoto H FAU - Fujino, Yusuke AU - Fujino Y FAU - Wang, Wei AU - Wang W FAU - Attizzani, Guilherme AU - Attizzani G FAU - Chamie, Daniel AU - Chamie D FAU - Simon, Daniel I AU - Simon DI FAU - Costa, Marco A AU - Costa MA LA - eng PT - Journal Article DEP - 20121012 PL - United States TA - Int J Cardiovasc Imaging JT - The international journal of cardiovascular imaging JID - 100969716 SB - IM MH - Aged MH - Coronary Angiography MH - Coronary Artery Disease/*diagnosis/*therapy MH - Coronary Vessels/diagnostic imaging/*pathology MH - Female MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Odds Ratio MH - Ohio MH - *Percutaneous Coronary Intervention/adverse effects/instrumentation MH - Predictive Value of Tests MH - Prospective Studies MH - Stents MH - *Tomography, Optical Coherence MH - Treatment Outcome EDAT- 2012/10/16 06:00 MHDA- 2013/12/18 06:00 CRDT- 2012/10/16 06:00 PHST- 2012/01/25 00:00 [received] PHST- 2012/09/25 00:00 [accepted] PHST- 2012/10/16 06:00 [entrez] PHST- 2012/10/16 06:00 [pubmed] PHST- 2013/12/18 06:00 [medline] AID - 10.1007/s10554-012-0135-0 [doi] PST - ppublish SO - Int J Cardiovasc Imaging. 2013 Apr;29(4):741-52. doi: 10.1007/s10554-012-0135-0. Epub 2012 Oct 12.